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BPDBA

Name: BPDBA
Brand: TargetMol
SKU: T26891
Price: 37 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T26891Cas No. 312281-74-6

BPDBA is an effective, selective, and non-competitive inhibitor of the betaine/GABA transporter (BGT-1), displaying inhibitory activity against human BGT-1 and mouse GAT2, with IC50 values of 20 μM and 35 μM, respectively.

BPDBA

🥰Excellent

Purity: 99.95%

Catalog No. T26891Cas No. 312281-74-6

Pack Size	Price	Availability
10 mg	$37	In Stock
25 mg	$78	In Stock
50 mg	$125	In Stock
100 mg	$201	In Stock
500 mg	$465	In Stock
1 mL x 10 mM (in DMSO)	$46	In Stock

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.95%

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Product Introduction

Bioactivity

Description	BPDBA is an effective, selective, and non-competitive inhibitor of the betaine/GABA transporter (BGT-1), displaying inhibitory activity against human BGT-1 and mouse GAT2, with IC50 values of 20 μM and 35 μM, respectively.
Targets&IC50	BGT1 (human):20 μM, GAT-2 (mice):35 μM

Chemical Properties

Molecular Weight	363.28
Formula	C₁₉H₂₀Cl₂N₂O
Cas No.	312281-74-6
Smiles	C(N1CCC(NC(=O)C2=C(Cl)C=C(Cl)C=C2)CC1)C3=CC=CC=C3
Relative Density.	no data available
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 27.5 mg/mL (75.7 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.7527 mL	13.7635 mL	27.5270 mL	137.6349 mL
5 mM	0.5505 mL	2.7527 mL	5.5054 mL	27.5270 mL
10 mM	0.2753 mL	1.3763 mL	2.7527 mL	13.7635 mL
20 mM	0.1376 mL	0.6882 mL	1.3763 mL	6.8817 mL
50 mM	0.0551 mL	0.2753 mL	0.5505 mL	2.7527 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc