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TargetMol | Compound Library

Ion Channel Targeted Library

Catalog No. L2300

Given the central functional role that the ion channel superfamily plays in human physiology, its membrane localization, and the diverse tissue distribution of different members of the family, it represents an attractive potential target class for drug discovery. Ion channelsplay a fundamental role in the way cells communicate. This communication between cells allows for the orchestration of physical and mental activities in humans. A number of diseases occur when ion channels do not function properly. Some examples are diabetes, neuropathic pain, cardiovascular diseases, asthma, epilepsy, and neurodegenerative disease, etc.

The Ion Channel Inhibitor Library by TargetMol, containing 1220 compounds targeting ion channels, can be used for research in ion channel, high throughput screening and high content screening for ion channel drug discovery.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L2300

Ion Channel Targeted Library

size

  • 1 mg
  • 10 µL x 10 mM (in DMSO)
  • 20 µL x 10 mM (in DMSO)
  • 30 µL x 10 mM (in DMSO)
  • 50 µL x 10 mM (in DMSO)
  • 100 µL x 10 mM (in DMSO)
  • 250 µL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 1220 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery;
  • Bioactivity and safety confirmed by pre-clinical research and clinical trials, and some of them are approved by FDA;
  • Targets include potassium channel, calcium channel, sodium channel, Proton pump, etc;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Targetmol Compound Libraries
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Library Customization | TargetMol Library Composition

Potassium Channel
Calcium Channel
Sodium Channel
GABA Receptor
TRP/TRPV Channel
AChR
iGluR
Apoptosis
Autophagy
Endogenous Metabolite
NMDAR
P2X Receptor
Parasite
Antibacterial
NF-κB
5-HT Receptor
Chloride channel
GluR
ROS
COX
Cytochromes P450
Adrenergic Receptor
ERK
Dopamine Receptor
Histamine Receptor
Reactive Oxygen Species
Akt
EGFR
HIV Protease
ATPase
Caspase
P-gp
NO Synthase
Drug Metabolite
p38 MAPK
Anti-infection
TNF
Antibiotic
Interleukin
DNA/RNA Synthesis
PI3K
Cannabinoid Receptor
Ferroptosis
PPAR
mTOR
HCN Channel
JNK
CaMK
Beta Amyloid
STAT
Cholinesterase (ChE)
Proton pump
PDE
GPCR
Na+/Ca2+ Exchanger
Influenza Virus
SARS-CoV
Antifungal
Mitochondrial Metabolism
PKC
Carbonic Anhydrase
Virus Protease
Topoisomerase
TLR
Lipoxygenase
MRP
Mitophagy
PKA
Dehydrogenase
MEK
PERK
Wnt/beta-catenin
VDAC
ABC Transporter
Nrf2
Bcl-2 Family
AMPK
VEGFR
IL Receptor
Antioxidant
Monoamine Transporter
HDAC
Serine/threonin kinase
LDL
Norepinephrine
GluCls
Tyrosinase
Transaminase
Microtubule Associated
TGF-beta/Smad
Phospholipase
Gamma-secretase
MMP
GPCR19
NADPH
transporter
Monoamine Oxidase
Sigma receptor
NOS
HCV Protease
Phosphatase
FXR
Opioid Receptor
Prostaglandin Receptor
PARP
cAMP
PAI-1
GlyT
Antifection
BCRP
HMG-CoA Reductase
Integrin
RAAS
GSK-3
Estrogen Receptor/ERR
Beta-Secretase
IκB/IKK
Amino Acids and Derivatives
Serine Protease
PAFR
Angiotensin-converting Enzyme (ACE)
Trk receptor
Piezo Channel
ROCK
Glucocorticoid Receptor
MT Receptor
Na-K-Cl cotransporter
DNA Methyltransferase
Thrombin
AhR
HSV
IGF-1R
Sirtuin
CFTR
Monocarboxylate transporter
Arrestin
Glutathione Peroxidase
Melatonin Receptor
Leukotriene Receptor
Aryl Hydrocarbon Receptor
DNA gyrase
CXCR
PTEN
STING
LRRK2
Pyroptosis
CGRP Receptor
PKM
c-Met/HGFR
c-Myc
CaSR
MAO
PAK
AIM2
GST
MDM-2/p53
Gap Junction Protein
Platelet aggregation
NOD
IRAK
ROS Kinase
ASBT
Histone Methyltransferase
Estrogen/progestogen Receptor
LPL Receptor
Glutaminase
RIP kinase
UGT
Androgen Receptor
FGFR
Protease-activated Receptor
Melanin-concentrating Hormone Receptor (MCHR)
Taste receptor
Reductase
Serotonin Transporter
CSF-1R
Myosin
CDK
Glucosidase
JAK
Epigenetic Reader Domain
Acyltransferase
HSP
FOXO
MicroRNA
Glucagon Receptor
DPP-4
RSV
c-Fms
Ras
S1P Receptor
Necroptosis
OCT
Lipid
NOD-like Receptor (NLR)
Src
LTR
N-Acetylglucosaminyltransferase
Nucleoside Antimetabolite/Analog
Anion Exchanger
CCR
glycosidase
DNA
Sodium-dependent phosphate transporter

Keywords