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Description | Amine-PEG-CH2COOH (MW 3400) is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis targeting chimeras (PROTACs). |
In vitro | PROTACs consist of two distinct ligands joined by a linker: one ligand targets an E3 ubiquitin ligase, while the other binds to the target protein. They utilize the intracellular ubiquitin-proteasome system for the selective degradation of target proteins[1]. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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