Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
20 μg | 20 days | $ 465.00 | |
100 μg | 20 days | $ 1,300.00 |
Description | Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway. |
Species | Rat |
Expression System | HEK293 |
Tag | N-terminal 10xHis-tagged and C-terminal Myc-tagged |
Accession Number | P32038 |
Synonyms | Adn, C3 convertase activator, Properdin factor D, Complement factor D, Endogenous vascular elastase, Df, Cfd, Adipsin |
Amino Acid | ILGGQEAMAHARPYMASVQVNGTHVCGGTLVDEQWVLSAAHCMDGVTKDEVVQVLLGAHSLSSPEPYKHLYDVQSVVLHPGSRPDSVEDDLMLFKLSHNASLGPHVRPLPLQREDREVKPGTLCDVAGWGVVTHAGRRPDVLQQLTVSIMDRNTCNLRTYHDGAITKNMMCAESNRRDTCRGDSGGPLVCGDAVEAVVTWGSRVCGNRRKPGVFTRVATYVPWIENVLSGNVSVNVTA Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request. |
Construction | 26-263 aa |
Protein Purity | > 90% as determined by SDS-PAGE. |
Molecular Weight | 29.8 kDa as predicted |
Formulation | Tris-based buffer,50% glycerol |
Reconstitution | A hardcopy of COA with reconstitution instructions is sent along with the products. Please refer to it for detailed information. |
Stability & Storage |
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. |
Shipping |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
Research Background | Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway. |
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Complement factor D Protein, Rat, Recombinant (His & Myc) Adn C3 convertase activator Properdin factor D Complement factor D Endogenous vascular elastase Df Cfd Adipsin recombinant recombinant-proteins proteins protein