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17-phenyl trinor Prostaglandin F2α methyl amide

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Catalog No. T37944Cas No. 155206-01-2
Alias 17-phenyl trinor Prostaglandin F2α methyl amide

17-phenyl trinor Prostaglandin F2α (17-phenyl trinor PGF2α) is a metabolically stable analog of PGF2α and is a potent agonist for the FP receptor, binding with a relative potency of 756% compared to that of PGF2α. The ethyl amide of 17-phenyl trinor PGF2α bimatoprost has been approved for use as an ocular hypotensive drug. 17-phenyl trinor PGF2α methyl amide is an analog of bimatoprost. Its biological and toxicological properties have not been evaluated.

17-phenyl trinor Prostaglandin F2α methyl amide

17-phenyl trinor Prostaglandin F2α methyl amide

😃Good
Catalog No. T37944Alias 17-phenyl trinor Prostaglandin F2α methyl amideCas No. 155206-01-2
17-phenyl trinor Prostaglandin F2α (17-phenyl trinor PGF2α) is a metabolically stable analog of PGF2α and is a potent agonist for the FP receptor, binding with a relative potency of 756% compared to that of PGF2α. The ethyl amide of 17-phenyl trinor PGF2α bimatoprost has been approved for use as an ocular hypotensive drug. 17-phenyl trinor PGF2α methyl amide is an analog of bimatoprost. Its biological and toxicological properties have not been evaluated.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$19835 days35 days
5 mg$88535 days35 days
10 mg$1,29035 days35 days
50 mg$3,20035 days35 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
17-phenyl trinor Prostaglandin F2α (17-phenyl trinor PGF2α) is a metabolically stable analog of PGF2α and is a potent agonist for the FP receptor, binding with a relative potency of 756% compared to that of PGF2α. The ethyl amide of 17-phenyl trinor PGF2α bimatoprost has been approved for use as an ocular hypotensive drug. 17-phenyl trinor PGF2α methyl amide is an analog of bimatoprost. Its biological and toxicological properties have not been evaluated.
Synonyms17-phenyl trinor Prostaglandin F2α methyl amide
Chemical Properties
Molecular Weight401.547
FormulaC24H35NO4
Cas No.155206-01-2
SmilesCNC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\[C@@H](O)CCc1ccccc1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMF: 25 mg/mL (62.26 mM), Sonication is recommended.
PBS (pH 7.2): 300 μg/mL, Sonication is recommended.
Ethanol: 50 mg/mL (124.52 mM), Sonication is recommended.
Acetonitrile: 3 mg/mL (7.47 mM), Sonication is recommended.
DMSO: 25 mg/mL (62.26 mM), Sonication is recommended.
Solution Preparation Table
Acetonitrile/DMF/DMSO/Ethanol
1mg5mg10mg50mg
1 mM2.4904 mL12.4518 mL24.9037 mL124.5184 mL
5 mM0.4981 mL2.4904 mL4.9807 mL24.9037 mL
DMF/DMSO/Ethanol
1mg5mg10mg50mg
10 mM0.2490 mL1.2452 mL2.4904 mL12.4518 mL
20 mM0.1245 mL0.6226 mL1.2452 mL6.2259 mL
50 mM0.0498 mL0.2490 mL0.4981 mL2.4904 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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