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LAIR1 Protein, Mouse, Recombinant (His)

TargetMol | SPR
Catalog No. TMPY-02598

LAIR1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.6 kDa and the accession number is Q8BG84-1.

LAIR1 Protein, Mouse, Recombinant (His)

LAIR1 Protein, Mouse, Recombinant (His)

TargetMol | SPR
Catalog No. TMPY-02598
LAIR1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.6 kDa and the accession number is Q8BG84-1.
Pack SizePriceAvailabilityQuantity
100 μg$6007-10 days
1 mg$3,9107-10 days
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Product Information

Biological Activity
Activity testing is not tested. It is theoretically active, but we cannot guarantee it.
Description
LAIR1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.6 kDa and the accession number is Q8BG84-1.
Species
Mouse
Expression System
HEK293 Cells
TagC-His
Accession NumberQ8BG84-1
Synonyms
leukocyte-associated immunoglobulin-like receptor 1,Lair-1,D7Bwg0421e,BB115266,5133400O11Rik
Construction
Gln22-Tyr141
Protein Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Molecular Weight14.6 kDa (Predicted); 30-42 kDa (Due to glycosylation)
EndotoxinLess than 1EU per μg by the LAL method.
FormulationLyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
Research Background
LAIR1 (leukocyte-associated Ig-like receptor-1, designated CD305) is an approximately 40 kDa type I transmembrane inhibitory glycoprotein belonging to the Ig superfamily.LAIR1 functions as an inhibitory receptor that plays a constitutive negative regulatory role on cytolytic function of natural killer (NK) cells, B-cells and T-cells. Activation by Tyr phosphorylation results in recruitment and activation of the phosphatases PTPN6 and PTPN11. It also reduces the increase of intracellular calcium evoked by B-cell receptor ligation.

Dose Conversion

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Please read the User Guide of Recombinant Proteins for more specific information.

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