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PG-116800

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Catalog No. T28394Cas No. 291533-11-4
Alias PGE-7113313, PGE 7113313, PG-530742, PG 530742

PG-116800 (PG-530742) is a matrix metalloproteinase (MMP) inhibitor. PG-116800 can be used in studies about the treatment of osteoarthritis.

PG-116800

PG-116800

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Purity: 99.66%
Catalog No. T28394Alias PGE-7113313, PGE 7113313, PG-530742, PG 530742Cas No. 291533-11-4
PG-116800 (PG-530742) is a matrix metalloproteinase (MMP) inhibitor. PG-116800 can be used in studies about the treatment of osteoarthritis.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$191In StockIn Stock
5 mg$480In StockIn Stock
10 mg$687In StockIn Stock
25 mg$1,080In StockIn Stock
50 mg$1,480In StockIn Stock
100 mg$1,990-In Stock
500 mg$3,920-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products.If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:99.66%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
PG-116800 (PG-530742) is a matrix metalloproteinase (MMP) inhibitor. PG-116800 can be used in studies about the treatment of osteoarthritis.
SynonymsPGE-7113313, PGE 7113313, PG-530742, PG 530742
Chemical Properties
Molecular Weight501.55
FormulaC24H27N3O7S
Cas No.291533-11-4
SmilesS(NC(CC#CCN1CCOCC1)C(O)=O)(=O)(=O)C2=CC=C(NC(=O)C3=CC=C(OC)C=C3)C=C2
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (99.69 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.9938 mL9.9691 mL19.9382 mL99.6910 mL
5 mM0.3988 mL1.9938 mL3.9876 mL19.9382 mL
10 mM0.1994 mL0.9969 mL1.9938 mL9.9691 mL
20 mM0.0997 mL0.4985 mL0.9969 mL4.9845 mL
50 mM0.0399 mL0.1994 mL0.3988 mL1.9938 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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