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Fosmidomycin sodium salt

Name: Fosmidomycin sodium salt
Brand: TargetMol
SKU: T11315
Price: 69 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T11315Cas No. 66508-37-0

Alias FR-31564 sodium salt

Fosmidomycin sodium salt (FR-31564 sodium salt) is an anti-infective antibiotic with anti-malarial activity that inhibits both Gram-negative and Gram-positive bacteria.

Fosmidomycin sodium salt

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Purity: 99.43%

Catalog No. T11315Alias FR-31564 sodium saltCas No. 66508-37-0

Fosmidomycin sodium salt (FR-31564 sodium salt) is an anti-infective antibiotic with anti-malarial activity that inhibits both Gram-negative and Gram-positive bacteria.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$69	-	In Stock
5 mg	$159	-	In Stock
10 mg	$237	-	In Stock
25 mg	$445	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.43%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Fosmidomycin sodium salt (FR-31564 sodium salt) is an anti-infective antibiotic with anti-malarial activity that inhibits both Gram-negative and Gram-positive bacteria.
In vitro	FR-31564 is a novel phosphonic acid antibiotic that exhibits activity against most Gram-negative and Gram-positive bacteria, except for mucoid Pseudomonas aeruginosa and glucose non-fermenting Gram-negative rods (excluding Pseudomonas aeruginosa).[1][2][3].
In vivo	After oral administration of 50 or 100 mg/kg of Fosmidomycin sodium salt, animals showed no parasites in their bodies, while treatment with 20 mg/kg resulted in a parasitemia rate of less than 1%. However, recurrence was observed when treatment was discontinued after 4 days. Complete cure was achieved in mice treated with 30 mg/kg of Fosmidomycin sodium salt 8 days.Animals apparently free of parasites are observed after intraperitoneal treatment[2].
Synonyms	FR-31564 sodium salt

Chemical Properties

Molecular Weight	205.08
Formula	C₄H₉NNaO₅P
Cas No.	66508-37-0
Smiles	O=CN(CCCP([O-])(O)=O)O.[Na+]
Relative Density.	no data available

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 20 mg/mL (97.52 mM), Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	4.8761 mL	24.3807 mL	48.7615 mL	243.8073 mL
5 mM	0.9752 mL	4.8761 mL	9.7523 mL	48.7615 mL
10 mM	0.4876 mL	2.4381 mL	4.8761 mL	24.3807 mL
20 mM	0.2438 mL	1.2190 mL	2.4381 mL	12.1904 mL
50 mM	0.0975 mL	0.4876 mL	0.9752 mL	4.8761 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc