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Anti-IL-1 alpha/IL-1A Polyclonal Antibody
(Synonyms: interleukin 1, α, interleukin 1, alpha, IL-1 α/IL1A) Copy Product Info
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Synonyms: interleukin 1, α, interleukin 1, alpha, IL-1 α/IL1A
Catalog No. TMAB-00931 Copy Product Info
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Anti-IL-1 alpha/IL-1A Polyclonal Antibody is a Rabbit antibody targeting IL-1 alpha/IL-1A. Anti-IL-1 alpha/IL-1A Polyclonal Antibody can be used in FCM,WB.
Anti-IL-1 alpha/IL-1A Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-IL-1 alpha/IL-1A Polyclonal Antibody is a Rabbit antibody targeting IL-1 alpha/IL-1A. Anti-IL-1 alpha/IL-1A Polyclonal Antibody can be used in FCM,WB. |
| Synonyms | interleukin 1, α, interleukin 1, alpha, IL-1 α/IL1A |
| Ig Type | IgG |
| Reactivity | Human,Mouse (predicted:Rat) |
| Application | |
| Recommended Dose | WB: 1:500-2000; FCM: 1ug/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted. Note=The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Interleukins (ILs) are a large group of cytokines that are produced mainly by leukocytes, although some are produced by certain phagocytes and auxiliary cells. Each IL acts on a specific, limited group of cells through a receptor specific for that IL. Interleukin 1 (IL1), originally known as lymphocyte activating factor (LAF), activates T cells and lymphocytes, which then proliferate and secrete interleukin 2. IL1 is primarily released from stimulated macrophages and monocytes, but also is released from several other cell types and is thought to play a key role in inflammatory and immune responses. The two closely related agents, interleukin 1 alpha (IL1 alpha) and interleukin 1 beta (IL1 beta) bind to the same cell surface receptor, elicit nearly identical biological responses and share 25% homology in their amino acid sequence. |
| Immunogen | KLH conjugated synthetic peptide: rat IL-1 Alpha |
| Antigen Species | Rat |
| Gene Name | IL1A |
| Gene ID | |
| Protein Name | Interleukin-1 alpha |
| Uniprot ID | |
| Function | Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. |
| Molecular Weight | Theoretical: 17, 31 kDa. Actual: 31 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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