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Uridine 5′-diphosphoglucose disodium salt

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Catalog No. T4743Cas No. 28053-08-9
Alias Uridine 5'-diphosphoglucose disodium sal, UDP-α-D-Glucose sodium salt, UDP-Glucose sodium salt, UDPG sodium salt

Uridine 5′-diphosphoglucose disodium salt (UDP-Glucose sodium salt) is an endogenous nucleotide sugar involved in glycosyltransferase reactions in metabolism. It is an agonist of the P2Y14 receptor (EC50 = 0.35 μM) and can also bind to and activate GPR17, inducing oligodendrocyte differentiation at a maximal concentration of 100 μM.

Uridine 5′-diphosphoglucose disodium salt

Uridine 5′-diphosphoglucose disodium salt

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Purity: 99.83%
Catalog No. T4743Alias Uridine 5'-diphosphoglucose disodium sal, UDP-α-D-Glucose sodium salt, UDP-Glucose sodium salt, UDPG sodium saltCas No. 28053-08-9
Uridine 5′-diphosphoglucose disodium salt (UDP-Glucose sodium salt) is an endogenous nucleotide sugar involved in glycosyltransferase reactions in metabolism. It is an agonist of the P2Y14 receptor (EC50 = 0.35 μM) and can also bind to and activate GPR17, inducing oligodendrocyte differentiation at a maximal concentration of 100 μM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
100 mg$42In StockIn Stock
500 mg$95In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.83%
Color:White
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Product Introduction

Bioactivity
Description
Uridine 5′-diphosphoglucose disodium salt (UDP-Glucose sodium salt) is an endogenous nucleotide sugar involved in glycosyltransferase reactions in metabolism. It is an agonist of the P2Y14 receptor (EC50 = 0.35 μM) and can also bind to and activate GPR17, inducing oligodendrocyte differentiation at a maximal concentration of 100 μM.
Targets&IC50
P2Y14 receptor:0.35 μM (EC50)
SynonymsUridine 5'-diphosphoglucose disodium sal, UDP-α-D-Glucose sodium salt, UDP-Glucose sodium salt, UDPG sodium salt
Chemical Properties
Molecular Weight610.27
FormulaC15H22N2Na2O17P2
Cas No.28053-08-9
Smiles[Na+].[Na+].OC[C@@H](OP(=O)(OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O)OP([O-])([O-])=O)[C@@H](O)[C@H](O)[C@@H](O)C=O
Relative Density.no data available
Storage & Solubility Information
Storagestore under nitrogen,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 125 mg/mL (204.83 mM), Sonication is recommended.
DMSO: 128.75 mg/mL (210.97 mM)
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 5 mg/mL (8.19 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM1.6386 mL8.1931 mL16.3862 mL81.9309 mL
5 mM0.3277 mL1.6386 mL3.2772 mL16.3862 mL
10 mM0.1639 mL0.8193 mL1.6386 mL8.1931 mL
20 mM0.0819 mL0.4097 mL0.8193 mL4.0965 mL
50 mM0.0328 mL0.1639 mL0.3277 mL1.6386 mL
100 mM0.0164 mL0.0819 mL0.1639 mL0.8193 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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