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Anti-ATP1A1 Polyclonal Antibody is a Rabbit antibody targeting ATP1A1. Anti-ATP1A1 Polyclonal Antibody can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $126 | 7-10 days | |
| 100 μL | $183 | 7-10 days | |
| 500 μL | $755 | 7-10 days |
| Description | Anti-ATP1A1 Polyclonal Antibody is a Rabbit antibody targeting ATP1A1. Anti-ATP1A1 Polyclonal Antibody can be used in WB. |
| Synonyms | Sodium/potassium-transporting ATPase subunit alpha-1, Sodium pump subunit alpha-1, Na(+)/K(+) ATPase alpha-1 subunit, EC 3.6.3.9, ATP1A1 |
| Ig Type | IgG |
| Reactivity | Human,Mouse (predicted:Rat,Chicken,Pig,Rabbit,GuineaPig) |
| Verified Activity | Sample: LOVO (Human) Cell Lysate at 30 μg Cerebrum (Mouse) Lysate at 40 μg Primary: Anti-ATP1A1 (TMAB-00165) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 113 kDa Observed band size: 113 kDa ![]() |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Multi-pass membrane protein. Melanosome. |
| Tissue Specificity | Found in most tissues. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+-ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May2009]. |
| Immunogen | KLH conjugated synthetic peptide: human ATP1A1 |
| Antigen Species | Human |
| Gene Name | ATP1A1 |
| Gene ID | |
| Protein Name | Sodium/potassium-transporting ATPase subunit alpha-1 |
| Uniprot ID | |
| Function | This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. |
| Molecular Weight | Theoretical: 113 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |

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