Shopping Cart
- Remove All
Your shopping cart is currently empty
Anti-CD73 Antibody (4N525)
😃Good
Catalog No. TMAY-01318
Alias NTE, NT5, NT, eNT, eN, E5NT, CD73, CALJA, 5'-nucleotidase, ecto (CD73)
Anti-CD73 Antibody (4N525) is a Rabbit antibody targeting CD73. Anti-CD73 Antibody (4N525) can be used in WB,IHC-P.
Anti-CD73 Antibody (4N525)
Anti-CD73 Antibody (4N525)
😃Good
Catalog No. TMAY-01318Alias NTE, NT5, NT, eNT, eN, E5NT, CD73, CALJA, 5'-nucleotidase, ecto (CD73)
Anti-CD73 Antibody (4N525) is a Rabbit antibody targeting CD73. Anti-CD73 Antibody (4N525) can be used in WB,IHC-P.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $268 | 7-10 days |
Bulk & Custom
Add to Cart
Questions
View MoreContact us for more batch information
Resource Download
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CD73 Antibody (4N525) is a Rabbit antibody targeting CD73. Anti-CD73 Antibody (4N525) can be used in WB,IHC-P. |
| Alias | NTE, NT5, NT, eNT, eN, E5NT, CD73, CALJA, 5'-nucleotidase, ecto (CD73) |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 4N525 |
| Reactivity | Human |
| Verified Activity | 1. Immunochemical staining of human NT5E in human spleen with rabbit monoclonal antibody (1:5000, formalin-fixed paraffin embedded sections). 2. Anti-NT5E rabbit monoclonal antibody at 1:500 dilution. -Lane A: NCI-H1299 Whole Cell Lysate. -Lane B: HepG2 Whole Cell Lysate. -Lane C: Hela Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution. -Developed using the Odyssey technique. -Performed under reducing conditions. -Predicted band size:63 kDa. -Observed band size:70 kDa(We are unsure as to the identity of these extra bands.) |
| Application | WB,IHC-P |
| Recommended Dose | WB: 1:500-1:2000; IHC-P: 1:2500-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human CD73 / NT5E (rh CD73 / NT5E; TMPY-01851; NP_002517.1; Met1-Lys547). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | 5'-nucleotidase, also known as NT5E, NTE, and CD73, is a cell membrane protein that belongs to the 5'-nucleotidase family. CD73 is a glycosylphosphatidylinositol (GPI) anchored purine salvage enzyme expressed on the surface of human T and B lymphocytes. CD73 catalyzes the conversion of purine and pyrimidine ribo- and deoxyribonucleoside monophosphates to the corresponding nucleosides. CD73 serves as a costimulatory molecule in activating T cells. CD73 generated adenosine functions in cell signaling in many physiologic systems, including intestinal epithelium, ischemic myocardium, and cholinergic synapses. CD73 might mediate lymphocyte-stromal cell interactions or condition the local microenvironment to facilitate lymphocyte development and/or function. In CD73-depleted cells, surface levels of the leukocyte adhesion molecules ICAM-1, VCAM-1, and E-selectin increase. CD73 produces extracellular adenosine, which then acts on G protein-coupled purinergic receptors to induce cellular responses. CD73 has also been reported to regulate the expression of pro-inflammatory molecules in mouse endothelium. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human CD73 / NT5E Protein (TMPY-01851) |
| Antigen Species | Human |
| Biology Area | Phosphatases and Regulators |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
Sci Citations
Calculator
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy Anti-CD73 Antibody (4N525) | purchase Anti-CD73 Antibody (4N525) | Anti-CD73 Antibody (4N525) cost | order Anti-CD73 Antibody (4N525)
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.