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Anti-GPRC5D Antibody-APC (8B50)
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Catalog No. TMAY-02844A
Alias GPRC5D
Anti-GPRC5D Antibody-APC (8B50) is a APC-conjugated Mouse antibody targeting GPRC5D. Anti-GPRC5D Antibody-APC (8B50) can be used in FCM.
Anti-GPRC5D Antibody-APC (8B50)
Anti-GPRC5D Antibody-APC (8B50)
😃Good
Catalog No. TMAY-02844AAlias GPRC5D
Anti-GPRC5D Antibody-APC (8B50) is a APC-conjugated Mouse antibody targeting GPRC5D. Anti-GPRC5D Antibody-APC (8B50) can be used in FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 T | $129 | 7-10 days | |
| 100 T | $258 | 7-10 days |
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Concentration:0.1 mg/mL
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Chemical Properties
| Description | Anti-GPRC5D Antibody-APC (8B50) is a APC-conjugated Mouse antibody targeting GPRC5D. Anti-GPRC5D Antibody-APC (8B50) can be used in FCM. |
| Synonyms | GPRC5D |
| Ig Type | Mouse IgG2b |
| Clone | 8B50 |
| Reactivity | Human |
| Specificity | Human GPRC5D |
| Verified Activity | Flow cytometric analysis of Human GPRC5D expression on CHO-K1 Cells were stained with APC-conjugated anti-Human GPRC5D. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| Application | |
| Recommended Dose | 5 μL/Test, 0.1 mg/mL |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human GPRC5D. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography, and conjugated with APC under optimum conditions, the unreacted APC was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| Research Background | Orphan G-protein-coupled receptor family C group 5 member D (GPRC5D) has seven transmembrane segments forming the core of the receptor, as well as an intracellular C-tail and an extracellular N-terminal domain. GPRC5D is highly and selectively expressed on the surface of CD138+ multiple myeloma (MM) cells, whereas in normal tissues, a much lower expression is limited to plasma cells and certain hard keratinizing tissues. This makes GPRC5D a promising marker for monitoring tumor load and a target antigen for MM-specific T cell-engaging therapies such as bispecific antibodies and CAR-T cells. |
| Conjucates | APC |
| Others Formats | Unconjugated/FITC/PE |
| Antibody Types Available | 4 |
| Immunogen | Recombinant Protein: Human GPRC5D Protein |
| Antigen Species | Human |
| Color | Transparent |
| Appearance | Liquid |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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