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Anti-SLAM/CD150 Polyclonal Antibody
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Catalog No. TMAB-01698
Alias SLAM, signaling lymphocytic activation molecule family member 1, CDw150, CD150
Anti-SLAM/CD150 Polyclonal Antibody is a Rabbit antibody targeting SLAM/CD150. Anti-SLAM/CD150 Polyclonal Antibody can be used in ELISA,IF,IHC-Fr,IHC-P,WB.
Anti-SLAM/CD150 Polyclonal Antibody
Anti-SLAM/CD150 Polyclonal Antibody
😃Good
Catalog No. TMAB-01698Alias SLAM, signaling lymphocytic activation molecule family member 1, CDw150, CD150
Anti-SLAM/CD150 Polyclonal Antibody is a Rabbit antibody targeting SLAM/CD150. Anti-SLAM/CD150 Polyclonal Antibody can be used in ELISA,IF,IHC-Fr,IHC-P,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-SLAM/CD150 Polyclonal Antibody is a Rabbit antibody targeting SLAM/CD150. Anti-SLAM/CD150 Polyclonal Antibody can be used in ELISA,IF,IHC-Fr,IHC-P,WB. |
| Synonyms | SLAM, signaling lymphocytic activation molecule family member 1, CDw150, CD150 |
| Ig Type | IgG |
| Reactivity | Mouse,Rat (predicted:Human,Dog,Pig,Cow,Horse,Sheep) |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Single-pass type I membrane protein. Note=Present on the surface of B-cells and T-cells. |
| Tissue Specificity | Constitutively expressed on peripheral blood memory T-cells, T-cell clones, immature thymocytes and a proportion of B-cells, and is rapidly induced on naive T-cells after activation. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | SLAM, a novel glycoprotein of 37kDa, designated SLAM (Signaling Lymphocyte Activation Molecule) or CDw150, belongs to the immunoglobulin gene superfamily and is involved in T cell stimulation. SLAM is constitutively expressed on peripheral blood memory T cells, T cell clones, immature thymocytes, and a proportion of B cells, and is rapidly induced on naive T cells after activation. Activated B cells express the membrane bound form of SLAM and the soluble and cytoplasmic isoforms of SLAM, and the expression levels of membrane bound SLAM on B cells are rapidly regulated after activation in vitro. It is suggested that signalling through homophilic SLAM-SLAM binding during B to B and B to T cell interactions enhances the expansion and differentiation of activated B cells. Reports suggest that the extracellular domain of CD150 is the receptor for the measles virus and acts as a co-activator on T cells and B cells. |
| Immunogen | KLH conjugated synthetic peptide: human CD150 |
| Antigen Species | Human |
| Gene Name | SLAMF1 |
| Gene ID | |
| Protein Name | Signaling lymphocytic activation molecule |
| Uniprot ID | |
| Biology Area | Endothelial Cell Markers,Non-lineage,Host Virus Interaction,HSC markers,Surface Molecules |
| Function | High-affinity self-ligand important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates. |
| Molecular Weight | Theoretical: 70 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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