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Anti-Ceramide synthase 2 Polyclonal Antibody is a Rabbit antibody targeting Ceramide synthase 2. Anti-Ceramide synthase 2 Polyclonal Antibody can be used in ELISA,IF,IHC-Fr,IHC-P,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
| Description | Anti-Ceramide synthase 2 Polyclonal Antibody is a Rabbit antibody targeting Ceramide synthase 2. Anti-Ceramide synthase 2 Polyclonal Antibody can be used in ELISA,IF,IHC-Fr,IHC-P,WB. |
| Synonyms | Tumor metastasis suppressor gene 1 protein, Tumor metastasis suppressor, TMSG-1, TMSG1, TMSG 1, SP260, SP 260, MGC987, Longevity assurance(LAG1 S. cerevisiae) homolog 2, LASS2, LASS 2, LAG1 longevity assurance homolog 2, LAG1 longevity assurance 2, L3 antibody LAG1 homolog ceramide synthase 2, FLJ10243, CerS2, CerS 2 |
| Ig Type | IgG |
| Reactivity | Rat (predicted:Human,Mouse,Chicken,Pig,Cow,Horse,Rabbit) |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. |
| Tissue Specificity | Expressed in kidney, liver, brain, heart, placenta and lung |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | LASS2 (LAG1 homolog, ceramide synthase 2) has sequence similarity to yeast longevity assurance gene 1. It is thought to be involved in sphingolipid synthesis. Expression of LASS2 is transiently increased during the period of active myelination and is specifically localized to white matter tracts of the brain, including the Schwann cells of sciatic nerves suggesting that LASS2 is important for the synthesis of dihydroceramide used for synthesis of myelin sphingolipids. Expression of LASS2 in hepatocellular carcinoma cell lines suppresses the growth of cancer cells. |
| Immunogen | KLH conjugated synthetic peptide: human LASS2 |
| Antigen Species | Human |
| Gene Name | CERS2 |
| Gene ID | |
| Protein Name | Ceramide synthase 2 |
| Uniprot ID | |
| Biology Area | Metabolism of lipids and lipoproteins,Tumor suppressors,Lipid metabolism,Lipid metabolism |
| Function | Suppresses the growth of cancer cells. May be involved in sphingolipid synthesis. |
| Molecular Weight | Theoretical: 45 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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