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M-myrmeciitoxin-Mp2b Protein, Myrmecia pilosula, Recombinant (GST & His)

(Synonyms: Pilosin-3 subunit b (Pilosulin-3b), M-myrmeciitoxin-Mp2b, M-MIITX-Mp2b, DELTA-myrtoxin-Mp1a B chain (Mp1a B chain)) Copy Product Info

Synonyms: Pilosin-3 subunit b (Pilosulin-3b), M-myrmeciitoxin-Mp2b, M-MIITX-Mp2b, DELTA-myrtoxin-Mp1a B chain (Mp1a B chain)

Catalog No. TMPH-03035 Copy Product Info
Heterodimer protein that may serve both defensive (pain-inducing) and predatory (insecticidal) roles. Has membrane-disrupting activity and shows induction of non-specific calcium influx into cells,. Shows broad-spectrum activity against a diverse range of bacteria, and cell lines, as well as hemolytic activity (EC(50)=2.18 uM). In vivo, shows moderate insecticidal activity against D.melanogaster and potent anthelmintic activity against the veterinary nematode H.contortus. In addition, intraplantar injection into mice induces nocifensive behavior and mechanical allodynia.
M-myrmeciitoxin-Mp2b Protein, Myrmecia pilosula, Recombinant (GST & His)
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Pack SizePriceUSA StockGlobal StockQuantity
5 µg$17620 days20 days
10 µg$29320 days20 days
20 µg$49120 days20 days
50 µg$92620 days20 days
100 µg$1,50020 days20 days
200 µg$1,83020 days20 days
500 µg$2,39020 days20 days
1 mg$2,96020 days20 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
Heterodimer protein that may serve both defensive (pain-inducing) and predatory (insecticidal) roles. Has membrane-disrupting activity and shows induction of non-specific calcium influx into cells,. Shows broad-spectrum activity against a diverse range of bacteria, and cell lines, as well as hemolytic activity (EC(50)=2.18 uM). In vivo, shows moderate insecticidal activity against D.melanogaster and potent anthelmintic activity against the veterinary nematode H.contortus. In addition, intraplantar injection into mice induces nocifensive behavior and mechanical allodynia.
Species
Myrmecia pilosula
Expression System
Baculovirus Insect Cells
TagN-GST, C-6xHis
Accession NumberP0C023
Amino AcidLIGLVSKGTCVLVKTVCKKVLKQ
Construction1-23 aa
Protein Purity
> 85% as determined by SDS-PAGE.
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
ReconstitutionReconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
SynonymsPilosin-3 subunit b (Pilosulin-3b), M-myrmeciitoxin-Mp2b, M-MIITX-Mp2b, DELTA-myrtoxin-Mp1a B chain (Mp1a B chain)
Research Background
Heterodimer protein that may serve both defensive (pain-inducing) and predatory (insecticidal) roles. Has membrane-disrupting activity and shows induction of non-specific calcium influx into cells,. Shows broad-spectrum activity against a diverse range of bacteria, and cell lines, as well as hemolytic activity (EC(50)=2.18 uM). In vivo, shows moderate insecticidal activity against D.melanogaster and potent anthelmintic activity against the veterinary nematode H.contortus. In addition, intraplantar injection into mice induces nocifensive behavior and mechanical allodynia.
Chemical Properties
Molecular Weight30.8 kDa (predicted)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

Related Tags: M-myrmeciitoxin-Mp2b Protein, Myrmecia pilosula, Recombinant (GST & His) chemical structure | M-myrmeciitoxin-Mp2b Protein, Myrmecia pilosula, Recombinant (GST & His) molecular weight