S100A9 Protein, Human, Recombinant

Name: S100A9 Protein, Human, Recombinant
Brand: TargetMol
SKU: TMPY-01330
Rating: 4.5 (1 reviews)

(Synonyms: S100 calcium binding protein A9, P14, NIF, MRP-14, MRP14, MIF, MAC387, LIAG, L1AG, CGLB, CFAG, CAGB, 60B8AG) Copy Product Info

Synonyms: S100 calcium binding protein A9, P14, NIF, MRP-14, MRP14, MIF, MAC387, LIAG, L1AG, CGLB, CFAG, CAGB, 60B8AG

Catalog No. TMPY-01330 Copy Product Info

S100A9 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 26 and 13 kDa and the accession number is P06702.

Pack Size	Price	USA Stock	Global Stock
5 µg	$79	7-10 days	7-10 days
10 µg	$129	7-10 days	7-10 days
20 µg	$208	7-10 days	7-10 days
50 µg	$419	7-10 days	7-10 days
100 µg	$812	7-10 days	7-10 days
200 µg	$1,230	7-10 days	7-10 days
500 µg	$2,530	7-10 days	7-10 days
1 mg	$5,300	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	This product displays no activity in cell-based assay.
Description	S100A9 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 26 and 13 kDa and the accession number is P06702.
Species	Human
Expression System	E. coli
Tag	Tag Free
Accession Number	P06702
Construction	A DNA sequence encoding the native form of human S100A9 (NP_002956.1) (Met 1-Pro 114) was expressed. Predicted N terminal: Met
Protein Purity	> 95 % as determined by SDS-PAGE
Endotoxin	Please contact us for more information.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Synonyms	S100 calcium binding protein A9, P14, NIF, MRP-14, MRP14, MIF, MAC387, LIAG, L1AG, CGLB, CFAG, CAGB, 60B8AG
Research Background	S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that the protein is 100% soluble in ammonium sulfate at neutral pH. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from the neural crest, chondrocytes, macrophages, dendritic cells, etc. S100 proteins have been implicated in a variety of intracellular and extracellular functions. They are involved in regulation of protein phosphorylation, transcription factors, the dynamics of cytoskeleton constituents, enzyme activities, cell growth and differentiation, and the inflammatory response. Protein S100-A9, also known as S100 calciumbinding protein A9, S100A9, and CAGB, is a member of the S-100 family. S100A9 is expressed by macrophages in acutely inflammed tissues and in chronic inflammation. It is also expressed in epithelial cells constitutively or induced during dermatoses. S100A9 is a calcium-binding protein. It has anti-microbial activity towards bacteria and fungi. The anti-microbial and proapoptotic activity of S100A9 is inhibited by zinc ions. S100A9 plays a role in the development of endotoxic shock in response to bacterial lipopolysaccharide (LPS). It promotes tubulin polymerization when unphosphorylated. It also promotes phagocyte migration and infiltration of granulocytes at sites of wounding. S100A9 plays a role as a proinflammatory mediator in acute and chronic inflammation and up-regulates the release of IL8 and cell-surface expression of ICAM1.

Chemical Properties

Molecular Weight

26 & 13 kDa (Non-reduced condition)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.