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m-PEG24-NH2

Name: m-PEG24-NH2
Brand: TargetMol
SKU: T18171
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T18171Cas No. 2151823-08-2

m-PEG24-NH2 is a PEG-based PROTAC linker that can be utilized in the synthesis of PROTACs (PROteolysis TArgeting Chimeras).

m-PEG24-NH2

🥰Excellent

Catalog No. T18171Cas No. 2151823-08-2

m-PEG24-NH2 is a PEG-based PROTAC linker that can be utilized in the synthesis of PROTACs (PROteolysis TArgeting Chimeras).

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
10 mg	$29	In Stock	In Stock
25 mg	Preferential	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Questions

Batch Information

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Purity:≥98%

Resource Download

COA HNMR

Product Introduction

Bioactivity

Description	m-PEG24-NH2 is a PEG-based PROTAC linker that can be utilized in the synthesis of PROTACs (PROteolysis TArgeting Chimeras).
In vitro	PROTACs utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins by containing two different ligands connected by a linker; one ligand binds to an E3 ubiquitin ligase, and the other binds to the target protein [1].

Chemical Properties

Molecular Weight	1088.32
Formula	C₄₉H₁₀₁NO₂₄
Cas No.	2151823-08-2
Smiles	C(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN)COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC
Relative Density.	no data available

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 10 mM, Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	0.9188 mL	4.5942 mL	9.1885 mL	45.9424 mL
5 mM	0.1838 mL	0.9188 mL	1.8377 mL	9.1885 mL
10 mM	0.0919 mL	0.4594 mL	0.9188 mL	4.5942 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc