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Anti-GPC3 Antibody (2M347)
😃Good
Catalog No. TMAH-00503
Alias SGBS1, SGBS, SGB, SDYS, OCI-5, MXR7, GTR2-2, Glypican 3, DGSX
Anti-GPC3 Antibody (2M347) is an antibody targeting GPC3. Anti-GPC3 Antibody (2M347) can be used in ELISA.
Anti-GPC3 Antibody (2M347)
Anti-GPC3 Antibody (2M347)
😃Good
Catalog No. TMAH-00503Alias SGBS1, SGBS, SGB, SDYS, OCI-5, MXR7, GTR2-2, Glypican 3, DGSX
Anti-GPC3 Antibody (2M347) is an antibody targeting GPC3. Anti-GPC3 Antibody (2M347) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $209 | 7-10 days | |
| 100 μL | $347 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Recombinant Monoclonal Application: ELISA Reactivity: Human |
| Alias | SGBS1, SGBS, SGB, SDYS, OCI-5, MXR7, GTR2-2, Glypican 3, DGSX |
| Ig Type | Human IgG1 |
| Clone | 2M347 |
| Reactivity | Human |
| Verified Activity | The Binding Activity of Human GPC3 with Anti-GPC3 recombinant Antibody Activity: Measured by its binding ability in a functional ELISA. Immobilized Human GPC3 at 2 μg/mL can bind Anti- GPC3 recombinant Antibody, the EC50 is 2.783-3.653 ng/mL. |
| Application | ELISA |
| Antibody Type | Monoclonal |
| Subcellular Localization | Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
| Research Background | Cell surface proteoglycan that bears heparan sulfate. Negatively regulates the hedgehog signaling pathway when attached via the GPI-anchor to the cell surface by competing with the hedgehog receptor PTC1 for binding to hedgehog proteins. Binding to the hedgehog protein SHH triggers internalization of the complex by endocytosis and its subsequent lysosomal degradation. Positively regulates the canonical Wnt signaling pathway by binding to the Wnt receptor Frizzled and stimulating the binding of the Frizzled receptor to Wnt ligands. Positively regulates the non-canonical Wnt signaling pathway. Binds to CD81 which decreases the availability of free CD81 for binding to the transcriptional repressor HHEX, resulting in nuclear translocation of HHEX and transcriptional repression. Inhibits the dipeptidyl peptidase activity of DPP4. Plays a role in limb patterning and skeletal development by controlling the cellular response to BMP4. Modulates the effects of growth factors BMP2, BMP7 and FGF7 on renal branching morphogenesis. Required for coronary vascular development. Plays a role in regulating cell movements during gastrulation. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human GPC3 Protein |
| Antigen Species | Human |
| Gene ID | 2719 |
| Uniprot ID | |
| Biology Area | Immunology |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
Sci Citations
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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