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Anti-BMP-4 Antibody (2T837)
😃Good
Catalog No. TMAY-01025
Alias ZYME, OFC11, MCOPS6, bone morphogenetic protein 4, BMP2B1, BMP2B
Anti-BMP-4 Antibody (2T837) is a Mouse antibody targeting BMP-4. Anti-BMP-4 Antibody (2T837) can be used in ELISA.
Anti-BMP-4 Antibody (2T837)
Anti-BMP-4 Antibody (2T837)
😃Good
Catalog No. TMAY-01025Alias ZYME, OFC11, MCOPS6, bone morphogenetic protein 4, BMP2B1, BMP2B
Anti-BMP-4 Antibody (2T837) is a Mouse antibody targeting BMP-4. Anti-BMP-4 Antibody (2T837) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $199 | 7-10 days |
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Product Introduction
Bioactivity
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Antigen Details
Chemical Properties
| Description | Anti-BMP-4 Antibody (2T837) is a Mouse antibody targeting BMP-4. Anti-BMP-4 Antibody (2T837) can be used in ELISA. |
| Alias | ZYME, OFC11, MCOPS6, bone morphogenetic protein 4, BMP2B1, BMP2B |
| Ig Type | Monoclonal Mouse IgG2b |
| Clone | 2T837 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human BMP4 (rh BMP4; TMPY-06842; P12644; Ser293-Arg408). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | BMP4 (bone morphogenetic protein-4)-directed differentiation of human embryonic stem cells (ESCd). Autophagy is a conserved catabolic process with complicated roles in tumor development. Bone morphogenetic protein 4 (BMP4), a member of the transforming growth factor (TGF-β) family of regulatory proteins, plays a crucial role in human malignancies. BMP4 treatment promoted HCC cells proliferation and induced autophagy. Mechanistic study revealed that the induction of autophagy by BMP4 was mediated through activating the JNK1/Bcl2 pathway. And the JNK1 inhibitor and knockdown of JNK1 could attenuate autophagy induced by BMP4 and eliminated BMP4-promoted HCC cells growth. BMP4 promoted HCC proliferation by autophagy activation through JNK1/Bcl-2 signaling. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human BMP4 Protein (TMPY-06842) |
| Antigen Species | Human |
| Biology Area | Early Mesodermal Lineage Markers, Cardiac Stem Cell Markers |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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