Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ipatasertib-NH2 dihydrochloride is a ligand for the target protein AKT in PROTAC INY-03-041. INY-03-041 consists of Ipatasertib-NH2, a ten-hydrocarbon linker, and the CRBN ligand Lenalidomide, which acts as an E3 ubiquitin ligase.
Pack Size | Availability | Price/USD | Quantity |
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25 mg | Inquiry | $ 1,520.00 |
Description | Ipatasertib-NH2 dihydrochloride is a ligand for the target protein AKT in PROTAC INY-03-041. INY-03-041 consists of Ipatasertib-NH2, a ten-hydrocarbon linker, and the CRBN ligand Lenalidomide, which acts as an E3 ubiquitin ligase. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Synonyms | RG7440-NH2 dihydrochloride, Ipatasertib-NH2 dihydrochloride, GDC-0068-NH2 dihydrochloride |
Molecular Weight | 488.84 |
Formula | C21H28Cl3N5O2 |
CAS No. | 1001264-73-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Ipatasertib-NH2 dihydrochloride 1001264-73-8 RG7440-NH2 dihydrochloride IpatasertibNH2 dihydrochloride RG7440-NH2 GDC-0068-NH2 Dihydrochloride GDC-0068-NH2 Ipatasertib NH2 dihydrochloride GDC-0068-NH2 dihydrochloride Ipatasertib-NH2 Ipatasertib-NH-2 dihydrochloride RG7440-NH2 Dihydrochloride Ipatasertib-NH2 Dihydrochloride inhibitor inhibit