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Anti-BMPRIB Antibody (5K774)
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Catalog No. TMAY-00856
Alias SKR6, CFK-43a, bone morphogenetic protein receptor, type IB, BMPR-IB, BMPR-1B, AV355320, ALK-6, Alk6, AI385617, Acvrlk6
Anti-BMPRIB Antibody (5K774) is a Mouse antibody targeting BMPRIB. Anti-BMPRIB Antibody (5K774) can be used in ELISA.
Anti-BMPRIB Antibody (5K774)
Anti-BMPRIB Antibody (5K774)
😃Good
Catalog No. TMAY-00856Alias SKR6, CFK-43a, bone morphogenetic protein receptor, type IB, BMPR-IB, BMPR-1B, AV355320, ALK-6, Alk6, AI385617, Acvrlk6
Anti-BMPRIB Antibody (5K774) is a Mouse antibody targeting BMPRIB. Anti-BMPRIB Antibody (5K774) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $199 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Mouse Monoclonal Application: ELISA Reactivity: Human |
| Alias | SKR6, CFK-43a, bone morphogenetic protein receptor, type IB, BMPR-IB, BMPR-1B, AV355320, ALK-6, Alk6, AI385617, Acvrlk6 |
| Ig Type | Mouse IgG1 |
| Clone | 5K774 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human ALK-6 / BMPR1B (rh ALK-6 / BMPR1B; TMPY-04367; NP_001194.1; Arg149-Leu502). The IgG fraction of the cell culture supernatant was purified by Protein A affinity. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | BMPR1B(bone morphogenetic protein receptor, type IB), also known as ALK6, is a member of the bone morphogenetic protein (BMP) receptor family. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. BMPR1B is the major transducer of signals in precartilaginous condensations as demonstrated in experiments using constitutively active BMPR1B receptors. BMPR1B is a more effective transducer of GDF5 than BMPR1A. Unlike BMPR1A null mice, which die at an early embryonic stage, BMPR1B null mice are viable. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human ALK-6 / BMPR1B protein (TMPY-04367) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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