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Anti-BMPRIB Antibody (5K774) (Alias: SKR6, CFK-43a, bone morphogenetic protein receptor, type IB, BMPR-IB|...)

Catalog No. TMAY-00856 Copy Product Info
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Anti-BMPRIB Antibody (5K774) is a Mouse antibody targeting BMPRIB. Anti-BMPRIB Antibody (5K774) can be used in ELISA.

Anti-BMPRIB Antibody (5K774)

Copy Product Info
🥰Excellent
Catalog No. TMAY-00856
Alias SKR6, CFK-43a, bone morphogenetic protein receptor, type IB, BMPR-IB, BMPR-1B, AV355320, ALK-6, Alk6, AI385617, Acvrlk6

Anti-BMPRIB Antibody (5K774) is a Mouse antibody targeting BMPRIB. Anti-BMPRIB Antibody (5K774) can be used in ELISA.

Anti-BMPRIB Antibody
(5K774)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$1997-10 days7-10 days
In stock · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-BMPRIB Antibody (5K774) is a Mouse antibody targeting BMPRIB. Anti-BMPRIB Antibody (5K774) can be used in ELISA.
SynonymsSKR6, CFK-43a, bone morphogenetic protein receptor, type IB, BMPR-IB, BMPR-1B, AV355320, ALK-6, Alk6, AI385617, Acvrlk6
Ig Type
Mouse IgG1
Clone
5K774
Reactivity
Human
Specificity
Human BMPRIB
No cross-reactivity in ELISA with
Insect cell lysate
Application
Recommended Dose
ELISA: 1:1000-1:2000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human ALK-6 / BMPR1B (rh ALK-6 / BMPR1B; TMPY-04367; NP_001194.1; Arg149-Leu502). The IgG fraction of the cell culture supernatant was purified by Protein A affinity.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundBMPR1B(bone morphogenetic protein receptor, type IB), also known as ALK6, is a member of the bone morphogenetic protein (BMP) receptor family. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. BMPR1B is the major transducer of signals in precartilaginous condensations as demonstrated in experiments using constitutively active BMPR1B receptors. BMPR1B is a more effective transducer of GDF5 than BMPR1A. Unlike BMPR1A null mice, which die at an early embryonic stage, BMPR1B null mice are viable.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human ALK-6 / BMPR1B protein (TMPY-04367)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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