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Omeprazole Sodium

🥰Excellent
Catalog No. T22391Cas No. 95510-70-6

Omeprazole Sodium is a proton pump inhibitor(PPI) and suppresses gastric acid secretion. Omeprazole Sodium is a potent neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor). Omeprazole Sodium shows competitive inhibition of CYP2C19 activity with a Ki of 2 to 6 μM. Omeprazole Sodium inhibits growth of Gram-positive and Gram-negative bacteria.

Omeprazole Sodium
Other Forms of Omeprazole Sodium:

Omeprazole Sodium

🥰Excellent
Purity: 99.84%
Catalog No. T22391Cas No. 95510-70-6
Omeprazole Sodium is a proton pump inhibitor(PPI) and suppresses gastric acid secretion. Omeprazole Sodium is a potent neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor). Omeprazole Sodium shows competitive inhibition of CYP2C19 activity with a Ki of 2 to 6 μM. Omeprazole Sodium inhibits growth of Gram-positive and Gram-negative bacteria.
Pack SizePriceAvailabilityQuantity
100 mg$41In Stock
200 mg$58In Stock
500 mg$97In Stock
1 mL x 10 mM (in DMSO)$45In Stock
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Purity:99.84%
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Product Introduction

Bioactivity
Description
Omeprazole Sodium is a proton pump inhibitor(PPI) and suppresses gastric acid secretion. Omeprazole Sodium is a potent neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor). Omeprazole Sodium shows competitive inhibition of CYP2C19 activity with a Ki of 2 to 6 μM. Omeprazole Sodium inhibits growth of Gram-positive and Gram-negative bacteria.
Targets&IC50
CYP2C19:2 to 6 μM(Ki)
In vivo
Omeprazole Sodium virtually eliminated intragastric acidity in all patients: the median 24 hour intragastric pH rose from 1.4 to 5.3 and the mean hourly hydrogen ion activity fell from 38.50 to 1.95 mmol(mEq)/1 (p less than 0.001)[1]
Chemical Properties
Molecular Weight367.4
FormulaC17H18N3NaO3S
Cas No.95510-70-6
SmilesO=S(CC1=NC=C(C)C(OC)=C1C)C2=NC3=C([N-]2)C=C(OC)C=C3.[Na+]
Relative Density.1.37g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 120 mg/mL (326.62 mM), Sonication is recommended.
H2O: 5.5 mg/mL (14.97 mM), Sonication is recommended.
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM2.7218 mL13.6091 mL27.2183 mL136.0915 mL
5 mM0.5444 mL2.7218 mL5.4437 mL27.2183 mL
10 mM0.2722 mL1.3609 mL2.7218 mL13.6091 mL
DMSO
1mg5mg10mg50mg
20 mM0.1361 mL0.6805 mL1.3609 mL6.8046 mL
50 mM0.0544 mL0.2722 mL0.5444 mL2.7218 mL
100 mM0.0272 mL0.1361 mL0.2722 mL1.3609 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

ProtonpumpProton pumpProton PumpPhospholipaseOmeprazole SodiumOmeprazoleInhibitorinhibitH-16868H16868H 16868CYP2C19BacterialAutophagy
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