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CD28H/TMIGD2 Protein, Human, Recombinant (His & Avi), Biotinylated

Catalog No. TMPY-05586
Synonyms: TMIGD2, IGPR-1, transmembrane and immunoglobulin domain containing 2, IGPR1, TPC1

The orthologue of human IGPR-1 is found only in eukaryotes, including primates, the guinea pig, canines, felines, dolphins, bovines, the llama, bats, the common shrew, and horses. Of interest, the IGPR-1 gene is absent in mouse and rat genomes. The immunoglobulin domain of IGPR-1 was predicted to be Ig V (variable) fold and was found to be highly similar to the Ig domain of myelin-associated glycoprotein.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy. CD28H/TMIGD2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 17.3 kDa and the accession number is Q96BF3-2.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
CD28H/TMIGD2 Protein, Human, Recombinant (His & Avi), Biotinylated
Pack Size Availability Price/USD Quantity
20 μg In stock $ 296.00
100 μg 5 days $ 690.00
200 μg 5 days $ 1,180.00
500 μg 5 days $ 2,380.00
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Biological Description
Technical Params
Product Properties
References and Literature
Biological Information Measured by its ability to bind Human HHLA2 (ECD, hFc Tag) in functional ELISA.
Description The orthologue of human IGPR-1 is found only in eukaryotes, including primates, the guinea pig, canines, felines, dolphins, bovines, the llama, bats, the common shrew, and horses. Of interest, the IGPR-1 gene is absent in mouse and rat genomes. The immunoglobulin domain of IGPR-1 was predicted to be Ig V (variable) fold and was found to be highly similar to the Ig domain of myelin-associated glycoprotein.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy. CD28H/TMIGD2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 17.3 kDa and the accession number is Q96BF3-2.
Species Human
Expression System HEK293 Cells
Tag His, Avi
Accession Number Q96BF3-2
Synonyms TMIGD2, IGPR-1, transmembrane and immunoglobulin domain containing 2, IGPR1, TPC1
Construction The Human TMIGD2 (NP_001162597.1) (Met1-Gly150) was expressed with a c-terminal polyhistidine tagged AVI tag at the C-terminus. The expressed protein was biotinylated in vivo by the Biotin-Protein ligase (BirA enzyme) which is co-expressed.
Protein Purity > 95 % as determined by SDS-PAGE.

Molecular Weight 17.3 kDa (predicted)
Endotoxin < 1.0 EU/μg of the protein as determined by the LAL method.
Formulation Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Shipping

In general, Lyophilized powders are shipping with blue ice.

Research Background The orthologue of human IGPR-1 is found only in eukaryotes, including primates, the guinea pig, canines, felines, dolphins, bovines, the llama, bats, the common shrew, and horses. Of interest, the IGPR-1 gene is absent in mouse and rat genomes. The immunoglobulin domain of IGPR-1 was predicted to be Ig V (variable) fold and was found to be highly similar to the Ig domain of myelin-associated glycoprotein.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy

References and Literature

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Keywords

CD28H/TMIGD2 Protein, Human, Recombinant (His & Avi), Biotinylated TMIGD2 TPC-1 TMIGD 2 TPC 1 IGPR 1 IGPR-1 transmembrane and immunoglobulin domain containing 2 IGPR1 TPC1 TMIGD-2 recombinant recombinant-proteins proteins protein

 

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