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Anti-S100A1 Antibody (1A890)

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Catalog No. TMAY-03200
Alias S100a, S100 calcium binding protein A1, S100, AI266795

Anti-S100A1 Antibody (1A890) is a Rabbit antibody targeting S100A1. Anti-S100A1 Antibody (1A890) can be used in IHC-P.

Anti-S100A1 Antibody (1A890)

Anti-S100A1 Antibody (1A890)

😃Good
Catalog No. TMAY-03200Alias S100a, S100 calcium binding protein A1, S100, AI266795
Anti-S100A1 Antibody (1A890) is a Rabbit antibody targeting S100A1. Anti-S100A1 Antibody (1A890) can be used in IHC-P.
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100 μL$269 7-10 days
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Product Introduction

Bioactivity
Description
Anti-S100A1 Antibody (1A890) is a Rabbit antibody targeting S100A1. Anti-S100A1 Antibody (1A890) can be used in IHC-P.
AliasS100a, S100 calcium binding protein A1, S100, AI266795
Ig Type
Monoclonal Rabbit IgG
Clone
1A890
Reactivity
Mouse
Verified Activity
1. Immunochemical staining of mouse S100A1 in mouse heart with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).

2. Immunochemical staining of human mouse S100A1 in mouse bone with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). Positive staining was localized to chondrocyte.
Application
IHC-P
Recommended Dose
IHC-P: 1:100-1:500
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Mouse S100A1 (rM S100A1; TMPY-02532; P56565; Gly2-Ser94).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundS100A1 is a Ca2+binding protein of the EF-hand type that belongs to the S100 protein family. S100 proteins consisting of at least 19 members exist as dimers in the cytoplasm and/or nucleus of a wide range of cells, and are involved in the regulation of a number of cellular processes such as cell-cycle progression and cell differentiation. This protein has been shown to function in the processes including stimulation of Ca2+-induced Ca2+release, inhibition of microtubule assembly, and inhibition of PKC-mediated phosphorylation. Phosphoglucomutase is a target protein whose activity is antagonistically regulated by S100A1, and recently, S100A1 is also identified as a potent molecular chaperone and a new member of the Hsp70/Hsp90 multichaperone complex. S100A1 displays a tissue-specific expression pattern with highest levels in myocardium and is considered to be an important regulator of cardiac contractility. Accordingly, reduced expression or mutations of S100A1 gene have been implicated in cardiomyopathies.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Mouse S100A1 protein (TMPY-02532)
Antigen Species
Mouse
Biology Area
Calcium-binding Proteins and Related Molecules
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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