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Lipopolysaccharides, from E. coli O111:B4
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Catalog No. TSW-00811
Lipopolysaccharides, from E. coli O111:B4 (LPS, from Escherichia coli (O111:B4)) are endotoxins and TLR-4 activators extracted from the bacterium E. coli O111:B4, classified as a smooth (S) type LPS. They exhibit a three-part structure comprised of the O antigen, R3-type core oligosaccharide, and lipid A. These lipopolysaccharides activate TLR-4 on immune cells, potentially causing significant gastric ailments. Furthermore, they can induce M1 polarization in murine macrophages.
Lipopolysaccharides, from E. coli O111:B4
Lipopolysaccharides, from E. coli O111:B4
😃Good
Catalog No. TSW-00811
Lipopolysaccharides, from E. coli O111:B4 (LPS, from Escherichia coli (O111:B4)) are endotoxins and TLR-4 activators extracted from the bacterium E. coli O111:B4, classified as a smooth (S) type LPS. They exhibit a three-part structure comprised of the O antigen, R3-type core oligosaccharide, and lipid A. These lipopolysaccharides activate TLR-4 on immune cells, potentially causing significant gastric ailments. Furthermore, they can induce M1 polarization in murine macrophages.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 mg | Inquiry | 7-10 days | |
| 50 mg | Inquiry | 7-10 days |
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Chemical Properties
| Description | Lipopolysaccharides, from E. coli O111:B4 (LPS, from Escherichia coli (O111:B4)) are endotoxins and TLR-4 activators extracted from the bacterium E. coli O111:B4, classified as a smooth (S) type LPS. They exhibit a three-part structure comprised of the O antigen, R3-type core oligosaccharide, and lipid A. These lipopolysaccharides activate TLR-4 on immune cells, potentially causing significant gastric ailments. Furthermore, they can induce M1 polarization in murine macrophages. |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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