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Preq1-Dihydrochloride

Name: Preq1-Dihydrochloride
Brand: TargetMol
SKU: T9012
Price: 39 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T9012Cas No. 86694-45-3

Alias pre-queuosine1 Dihydrochloride

Preq1-Dihydrochloride (pre-queuosine1 Dihydrochloride) is an intermediate of the queuosine pathway, it binds with high affinity to the aptamer of PreQ1 riboswitch, which attenuates protein expression.

Preq1-Dihydrochloride

🥰Excellent

Purity: 99.46%

Catalog No. T9012Alias pre-queuosine1 DihydrochlorideCas No. 86694-45-3

Pack Size	Price	Availability
1 mg	$39	In Stock
5 mg	$89	In Stock
10 mg	$128	In Stock
25 mg	$219	In Stock
50 mg	$326	In Stock
100 mg	$486	In Stock
500 mg	$1,060	In Stock

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Batch Information

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Purity:99.46%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Preq1-Dihydrochloride (pre-queuosine1 Dihydrochloride) is an intermediate of the queuosine pathway, it binds with high affinity to the aptamer of PreQ1 riboswitch, which attenuates protein expression.
Synonyms	pre-queuosine1 Dihydrochloride

Chemical Properties

Molecular Weight	252.1
Formula	C₇H₁₁Cl₂N₅O
Cas No.	86694-45-3
Smiles	Cl.Cl.NCc1c[nH]c2nc(N)[nH]c(=O)c12
Relative Density.	no data available
Color	Brown
Appearance	Solid

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 10 mg/mL (39.67 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.9667 mL	19.8334 mL	39.6668 mL	198.3340 mL
5 mM	0.7933 mL	3.9667 mL	7.9334 mL	39.6668 mL
10 mM	0.3967 mL	1.9833 mL	3.9667 mL	19.8334 mL
20 mM	0.1983 mL	0.9917 mL	1.9833 mL	9.9167 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc