IL-17A Protein, Human, Recombinant (His)

Name: IL-17A Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPS-00066
Rating: 4.5 (1 reviews)

(Synonyms: IL17A, CTLA-8) Copy Product Info

Synonyms: IL17A, CTLA-8

Catalog No. TMPS-00066 Copy Product Info

IL-17A Protein, Human, Recombinant (His) is expressed in CHO Cells. The accession number is Q16552.

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Pack Size	Price	USA Stock	Global Stock
5 µg	$85	7-10 days	7-10 days
10 µg	$138	-	In Stock
20 µg	$197	7-10 days	7-10 days
50 µg	$339	-	In Stock
100 µg	$543	7-10 days	7-10 days
200 µg	$877	7-10 days	7-10 days
500 µg	$1,650	7-10 days	7-10 days
1 mg	$2,680	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:> 95% as determined by SDS-PAGE

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	ED 50 < 10.0 ng/ml. Measured by its ability to induce IL-6 secretion by NIH 3T3 mouse embryonic fibroblast cells, corresponding to a specific activity of > 1.0 × 10 5 units/mg.
Description	IL-17A Protein, Human, Recombinant (His) is expressed in CHO Cells. The accession number is Q16552.
Species	Human
Expression System	CHO Cells
Tag	His
Accession Number	Q16552
Construction	Gly24-Ala155
Protein Purity	> 95% as determined by SDS-PAGE
Endotoxin	< 0.2 EU/μg of protein as determined by the LAL method.
Formulation	Lyophilized from a 0.2 μm filtered solution in PBS.
Reconstitution	Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	IL17A, CTLA-8
Research Background	Interleukin-17A (IL-17A),also known as CTLA-8 and IL-17, is a proinflammatory cytokine belonging to the IL-17 family. It is secreted by Th17 cells, gamma/delta T cells, NK cells and neutrophils. IL-17A signals through IL-17 receptor A in a complex with receptor C or D to regulate NF-kappaB and MAP kinase activities. IL-17A plays important roles in the anti-microbial response and chronic inflammation. It stimulates the production of IL-6, IL-8 and G-CSF in epithelial and endothelial cells, and induces the expression of ICAM-1 in fibroblasts. Clinically, IL-17A has been associated with inflammatory diseases, such as rheumatoid arthritis, psoriasis and multiple sclerosis.

Chemical Properties

Molecular Weight

14~22 kDa (Reducing conditions)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.