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2-Amino-3-iodopyridine (3-Iodopyridin-2-amine) can couple with formyl derivatives under copper-catalyzed indole synthesis conditions, followed by constructing azidoindole analogs through copper-mediated conjugate addition. Its nucleophilicity is lower than the corresponding anilines used in indole synthesis, which may pose a potential obstacle for future synthesis.
Description | 2-Amino-3-iodopyridine (3-Iodopyridin-2-amine) can couple with formyl derivatives under copper-catalyzed indole synthesis conditions, followed by constructing azidoindole analogs through copper-mediated conjugate addition. Its nucleophilicity is lower than the corresponding anilines used in indole synthesis, which may pose a potential obstacle for future synthesis. |
Molecular Weight | 220.0111 |
Formula | C5H5IN2 |
Cas No. | 104830-06-0 |
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