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EP2 receptor antagonist-2

🥰Excellent
Catalog No. T67946Cas No. 615273-95-5

EP2 receptor antagonist-2 (CID891729) is a compound that blocks EP2 receptor activation by PGE2 and reduces lactate dehydrogenase (LDH) release induced by N-methyl-D-aspartate (NMDA).

EP2 receptor antagonist-2

EP2 receptor antagonist-2

🥰Excellent
Purity: 99.95%
Catalog No. T67946Cas No. 615273-95-5
EP2 receptor antagonist-2 (CID891729) is a compound that blocks EP2 receptor activation by PGE2 and reduces lactate dehydrogenase (LDH) release induced by N-methyl-D-aspartate (NMDA).
Pack SizePriceAvailabilityQuantity
1 mg$45In Stock
5 mg$106In Stock
10 mg$172In Stock
25 mg$297In Stock
50 mg$442In Stock
100 mg$638In Stock
500 mg$1,330In Stock
1 mL x 10 mM (in DMSO)$153In Stock
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Purity:99.95%
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Product Introduction

Bioactivity
Description
EP2 receptor antagonist-2 (CID891729) is a compound that blocks EP2 receptor activation by PGE2 and reduces lactate dehydrogenase (LDH) release induced by N-methyl-D-aspartate (NMDA).
Chemical Properties
Molecular Weight309.29
FormulaC15H14F3N3O
Cas No.615273-95-5
SmilesFC(F)(F)c1cc(nc(n1)N1CCOCC1)-c1ccccc1
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 112.5 mg/mL (363.7 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.2332 mL16.1661 mL32.3321 mL161.6606 mL
5 mM0.6466 mL3.2332 mL6.4664 mL32.3321 mL
10 mM0.3233 mL1.6166 mL3.2332 mL16.1661 mL
20 mM0.1617 mL0.8083 mL1.6166 mL8.0830 mL
50 mM0.0647 mL0.3233 mL0.6466 mL3.2332 mL
100 mM0.0323 mL0.1617 mL0.3233 mL1.6166 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

ProstaglandinReceptorProstaglandin Receptor
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