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PHYTOL

Name: PHYTOL
Brand: TargetMol
SKU: T3254
Price: 42 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T3254Cas No. 150-86-7

Alias trans-Phytol, (E)-Phytol

PHYTOL (trans-Phytol) , a diterpene alcohol from chlorophyll widely used as a food additive and in medicinal fields, shows antinociceptive and antioxidant activities as well as anti-inflammatory and antiallergic effects. It is a specific activator of PPARα.

PHYTOL

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Purity: 99.62%

Catalog No. T3254Alias trans-Phytol, (E)-PhytolCas No. 150-86-7

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 g	$42	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$46	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:99.62%

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Product Introduction

PHYTOL AI Summary

PHYTOL exhibits antitubercular activity against Mycobacterium tuberculosis H37Rv and H37Rv ATCC 27294 with minimum inhibitory concentrations (MIC) of 100.0 µg/mL and 1.56 µg/mL, respectively. It shows low cytotoxic activity against human KB, Lu1, HepG2, and MCF7 cell lines with an IC50 greater than 100,000.0 nM. Additionally, PHYTOL demonstrates substrate activity at 6xHis-tagged Streptococcus mutans UdpK expressed in Escherichia coli BL-21(DE3), with an activity level of 5.6 µmol/mg/min as measured in a PK/LDH coupled assay..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	PHYTOL (trans-Phytol) , a diterpene alcohol from chlorophyll widely used as a food additive and in medicinal fields, shows antinociceptive and antioxidant activities as well as anti-inflammatory and antiallergic effects. It is a specific activator of PPARα.
Synonyms	trans-Phytol, (E)-Phytol

Chemical Properties

Molecular Weight	296.53
Formula	C₂₀H₄₀O
Cas No.	150-86-7
Smiles	[C@@H](CCC[C@@H](CCCC(C)C)C)(CCC/C(=C/CO)/C)C
Relative Density.	0.859. Temperature:20 °C.

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 2.97 mg/mL (10.02 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 1 mg/mL (3.37 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.3723 mL	16.8617 mL	33.7234 mL	168.6170 mL
5 mM	0.6745 mL	3.3723 mL	6.7447 mL	33.7234 mL
10 mM	0.3372 mL	1.6862 mL	3.3723 mL	16.8617 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc