Powder: -20°C for 3 years | In solvent: -80°C for 1 year
EFdA-TP tetraammonium is an influential nucleoside reverse transcriptase (RT) inhibitor that effectively prevents RT-mediated DNA synthesis by acting as an immediate or delayed chain terminator (ICT or DCT). Additionally, EFdA-TP tetraammonium exhibits multiple mechanisms of inhibiting HIV-1 RT[1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | Inquiry | $ 481.00 | |
5 mg | Inquiry | $ 1,190.00 |
Description | EFdA-TP tetraammonium is an influential nucleoside reverse transcriptase (RT) inhibitor that effectively prevents RT-mediated DNA synthesis by acting as an immediate or delayed chain terminator (ICT or DCT). Additionally, EFdA-TP tetraammonium exhibits multiple mechanisms of inhibiting HIV-1 RT[1]. |
In vitro | EFdA-TP tetraammonium, at concentrations ranging from 0.05 to 10 μM and applied for 15 minutes, serves as an effective inhibitor of reverse transcriptase (RT)-catalyzed DNA synthesis, functioning through immediate or delayed chain termination mechanisms[1]. It acts as a translocation-defective RT inhibitor, significantly reducing the pace of DNA synthesis and essentially serving as an immediate chain terminator. Additionally, EFdA-TP tetraammonium has the capability to operate as a delayed chain terminator, permitting the incorporation of one more dNTP prior to halting DNA synthesis[1]. |
Molecular Weight | N/A |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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