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Anti-IL-36 alpha/IL-1F6 Antibody (3I744)
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Catalog No. TMAY-03104
Alias interleukin 36, α, interleukin 36, alpha, IL36A, IL36 α/IL-1F6, IL-1F6, IL1F6, IL1E, IL1(ε), IL1(EPSILON), FIL1E, FIL1(ε), FIL1(EPSILON), FIL1, FIL, 1E
Anti-IL-36 alpha/IL-1F6 Antibody (3I744) is a Rabbit antibody targeting IL-36 alpha/IL-1F6. Anti-IL-36 alpha/IL-1F6 Antibody (3I744) can be used in ELISA.
Anti-IL-36 alpha/IL-1F6 Antibody (3I744)
Anti-IL-36 alpha/IL-1F6 Antibody (3I744)
😃Good
Catalog No. TMAY-03104Alias interleukin 36, α, interleukin 36, alpha, IL36A, IL36 α/IL-1F6, IL-1F6, IL1F6, IL1E, IL1(ε), IL1(EPSILON), FIL1E, FIL1(ε), FIL1(EPSILON), FIL1, FIL, 1E
Anti-IL-36 alpha/IL-1F6 Antibody (3I744) is a Rabbit antibody targeting IL-36 alpha/IL-1F6. Anti-IL-36 alpha/IL-1F6 Antibody (3I744) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $269 | 7-10 days |
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Chemical Properties
| Description | Anti-IL-36 alpha/IL-1F6 Antibody (3I744) is a Rabbit antibody targeting IL-36 alpha/IL-1F6. Anti-IL-36 alpha/IL-1F6 Antibody (3I744) can be used in ELISA. |
| Alias | interleukin 36, α, interleukin 36, alpha, IL36A, IL36 α/IL-1F6, IL-1F6, IL1F6, IL1E, IL1(ε), IL1(EPSILON), FIL1E, FIL1(ε), FIL1(EPSILON), FIL1, FIL, 1E |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 3I744 |
| Reactivity | Mouse |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse IL-1F6 (rM IL-1F6; TMPY-01956; Q9JLA2-1; Met1-His160). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Interleukin-1 family member 6 (IL-1F6), also known as interleukin 36, alpha (IL36A), is a pro-inflammatory cytokine that plays an important role in innate and adaptive immunity. IL-1F6 activates MAPK and NF-kB pathways and is produced by many different cells. This cytokine is a family member of interleukin-1 (IL-1) and plays an important role in the pathophysiology of several diseases. It has been reported that IL-1F6 and IL-1F8, in addition to IL-1F9, activate the pathway leading to NF-kappaB in an IL-1Rrp2-dependent manner in Jurkat cells as well as in multiple other human and mouse cell lines. Activation of the pathway leading to NF-kappaB by IL-1F6 and IL-1F8 follows a similar time course to activation by IL-1beta, suggesting that signaling by the novel family members occurs through a direct mechanism. In a mammary epithelial cell line, NCI/ADR-RES, which naturally expresses IL-1Rrp2, all three cytokines signal without further receptor transfection. IL-1Rrp2 antibodies block activation of the pathway leading to NF-kappaB by IL-1F6, IL-1F8, and IL-1F9 in both Jurkat and NCI/ADR-RES cells. Thus IL-1F6, IL-1F8, and IL-1F9 signal through IL-1Rrp2 and IL-1RAcP. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Mouse IL-1F6 Protein (TMPY-01956) |
| Antigen Species | Mouse |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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