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Claudin-18.2 Protein, Human, Recombinant (Insect, His)
Catalog No. TMPS-00018
Claudin-18.2 Protein, Human, Recombinant (Insect, His) is expressed in Baculovirus Insect Cells. The accession number is P56856-2.
Claudin-18.2 Protein, Human, Recombinant (Insect, His)
Catalog No. TMPS-00018
Claudin-18.2 Protein, Human, Recombinant (Insect, His) is expressed in Baculovirus Insect Cells. The accession number is P56856-2.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 μg | $622 | 7-10 days | |
| 100 μg | $4,230 | 7-10 days | |
| 1 mg | Inquiry | 7-10 days |
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Product Information
| Biological Activity | Immobilized CLDN18.2, His, Human (Cat. No.: Z03504) at 1.0 μg/mL (100μl/well). Dose response curve for anti-Claudin 18.2 Antibody with the EC 50 of 13.75ng/mL determined by ELISA. |
| Description | Claudin-18.2 Protein, Human, Recombinant (Insect, His) is expressed in Baculovirus Insect Cells. The accession number is P56856-2. |
| Species | Human |
| Expression System | Baculovirus Insect Cells |
| Tag | His |
| Accession Number | P56856-2 |
| Synonyms | SFTPJ,SFTA5,CLDN18,Claudin-18,claudin 18 |
| Construction | Met1-Lys207 |
| Protein Purity | > 80% as determined by SDS-PAGE |
| Molecular Weight | 27.7 kDa (Predicted) |
| Formulation | Supplied as a solution in 50 mM Hepes, 500 mM NaCl, 10% glycerol, 0.2% DDM, 0.04% CHS, pH 7.5. |
| Stability & Storage | Upon receiving, this product remains stable for up to 6 months at -80°C. Please avoid repeated freeze-thaw cycles. |
| Shipping | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
| Research Background | Claudin-18 is a protein that in humans is encoded by the CLDN18 gene. CLDN18 belongs to the large claudin family of proteins, which form tight junction strands in epithelial cells. The Expression of Isoform A2 (CLDN18.2) is restricted to the stomach mucosa where it is predominantly observed in the epithelial cells of the pit region and the base of the gastric glands including exocrine and endocrine cells (at protein level). CLDN18.2 is founded to be abundant in gastric tumors, Experimental antibody IMAB362 targets Claudin 18.2 to help treat gastric cancers. |
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