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Saikosaponin B2

🥰Excellent
Catalog No. T3810Cas No. 58316-41-9

Saikosaponin B2 acts on HCV E2 and inhibits infection by several genotypic strains and prevents binding of serum-derived HCV onto hepatoma cells. Saikosaponin B2 (5 μM) induces differentiation of B16 melanoma cells, with potentiation of expressions of tyrosinase and melanogenesis.

Saikosaponin B2

Saikosaponin B2

🥰Excellent
Purity: 99.59%
Catalog No. T3810Cas No. 58316-41-9
Saikosaponin B2 acts on HCV E2 and inhibits infection by several genotypic strains and prevents binding of serum-derived HCV onto hepatoma cells. Saikosaponin B2 (5 μM) induces differentiation of B16 melanoma cells, with potentiation of expressions of tyrosinase and melanogenesis.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$36In StockIn Stock
5 mg$79In StockIn Stock
10 mg$137In StockIn Stock
25 mg$252In StockIn Stock
50 mg$376In StockIn Stock
100 mg$565-In Stock
500 mg$1,230-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.59%
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Product Introduction

Bioactivity
Description
Saikosaponin B2 acts on HCV E2 and inhibits infection by several genotypic strains and prevents binding of serum-derived HCV onto hepatoma cells. Saikosaponin B2 (5 μM) induces differentiation of B16 melanoma cells, with potentiation of expressions of tyrosinase and melanogenesis.
Chemical Properties
Molecular Weight780.98
FormulaC42H68O13
Cas No.58316-41-9
Smiles[H][C@@]1(O[C@H]2[C@@H](O)[C@@H](C)O[C@@]([H])(O[C@H]3CC[C@@]4(C)[C@@]([H])(CC[C@]5(C)[C@]4([H])C=CC4=C6CC(C)(C)CC[C@]6(CO)[C@H](O)C[C@@]54C)[C@]3(C)CO)[C@@H]2O)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O
Relative Density.1.35 g/cm3 (Predicted)
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (64.02 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (2.56 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.2804 mL6.4022 mL12.8044 mL64.0221 mL
5 mM0.2561 mL1.2804 mL2.5609 mL12.8044 mL
10 mM0.1280 mL0.6402 mL1.2804 mL6.4022 mL
20 mM0.0640 mL0.3201 mL0.6402 mL3.2011 mL
50 mM0.0256 mL0.1280 mL0.2561 mL1.2804 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

Saikosaponin B-2Saikosaponin B2Saikosaponin B 2InhibitorinhibitHepatitis C virusHCVProteaseHCV ProteaseHCV
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