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PE(18:1(9Z)/0:0)

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Catalog No. T37280Cas No. 89576-29-4

PE(18:1(9Z)/0:0) is a naturally-occurring lysophospholipid and an analog of plasmalogen lysophosphatidylethanolamine. PE(18:1(9Z)/0:0) induces transient increases in intracellular calcium in PC12 rat neuronal cells in a concentration-dependent manner. PE(18:1(9Z)/0:0) increases the production of IL-4 and IL-2, but not IFN-γ. In mouse serum, PE(18:1(9Z)/0:0) (1 μg/animal) induces the T helper 2 response. PE(18:1(9Z)/0:0) levels increase in interscapular brown adipose tissue in mice following three-day cold exposure.

PE(18:1(9Z)/0:0)

PE(18:1(9Z)/0:0)

😃Good
Purity: 99.45%
Catalog No. T37280Cas No. 89576-29-4
PE(18:1(9Z)/0:0) is a naturally-occurring lysophospholipid and an analog of plasmalogen lysophosphatidylethanolamine. PE(18:1(9Z)/0:0) induces transient increases in intracellular calcium in PC12 rat neuronal cells in a concentration-dependent manner. PE(18:1(9Z)/0:0) increases the production of IL-4 and IL-2, but not IFN-γ. In mouse serum, PE(18:1(9Z)/0:0) (1 μg/animal) induces the T helper 2 response. PE(18:1(9Z)/0:0) levels increase in interscapular brown adipose tissue in mice following three-day cold exposure.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$37In StockIn Stock
5 mg$79In StockIn Stock
10 mg$142In StockIn Stock
25 mg$269In StockIn Stock
50 mg$398-In Stock
100 mg$593-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.45%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
PE(18:1(9Z)/0:0) is a naturally-occurring lysophospholipid and an analog of plasmalogen lysophosphatidylethanolamine. PE(18:1(9Z)/0:0) induces transient increases in intracellular calcium in PC12 rat neuronal cells in a concentration-dependent manner. PE(18:1(9Z)/0:0) increases the production of IL-4 and IL-2, but not IFN-γ. In mouse serum, PE(18:1(9Z)/0:0) (1 μg/animal) induces the T helper 2 response. PE(18:1(9Z)/0:0) levels increase in interscapular brown adipose tissue in mice following three-day cold exposure.
Chemical Properties
Molecular Weight479.59
FormulaC23H46NO7P
Cas No.89576-29-4
SmilesCCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)COP(O)(=O)OCCN
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
Chloroform: 3 mg/mL (6.26 mM), Sonication is recommended.
Ethanol: 2.3 mg/mL (4.8 mM)
DMSO: < 0.55 mg/mL (insoluble or slightly soluble)
Solution Preparation Table
Ethanol/Chloroform
1mg5mg10mg50mg
1 mM2.0851 mL10.4256 mL20.8511 mL104.2557 mL
Chloroform
1mg5mg10mg50mg
5 mM0.4170 mL2.0851 mL4.1702 mL20.8511 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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