Immunoglobulin Superfamily Member 8 (IGSF8) is a single-pass membrane protein. IGSF8 contains four Ig-like C2 type domains. The Ig-like C2-type domains 3 and 4 are required for interactions with CD81. IGSF8 may regulate proliferation and differentiation of keratinocytes. IGSF8 may participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain. It also may play a role on integrin-dependent morphology and motility functions.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 μg | 5 days | $ 160.00 | |
50 μg | 5 days | $ 487.00 | |
500 μg | 5 days | $ 2,970.00 | |
1 mg | 5 days | $ 4,480.00 |
Description | Immunoglobulin Superfamily Member 8 (IGSF8) is a single-pass membrane protein. IGSF8 contains four Ig-like C2 type domains. The Ig-like C2-type domains 3 and 4 are required for interactions with CD81. IGSF8 may regulate proliferation and differentiation of keratinocytes. IGSF8 may participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain. It also may play a role on integrin-dependent morphology and motility functions. |
Species | Human |
Expression System | Human Cells |
Tag | C-Fc |
Accession Number | Q969P0 |
Synonyms | KCT-4, EWI2, CD81P3, CD316, IGSF8, Glu-Trp-Ile EWI Motif-Containing Protein 2, CD81 Partner 3, Keratinocytes-Associated Transmembrane Protein 4, Immunoglobulin Superfamily Member 8, PGRL, KCT4, LIR-D1, EWI-2, Prostaglandin Regulatory-Like Protein |
Amino Acid | Arg28-Thr579 |
Construction | Recombinant Human Immunoglobulin Superfamily Member 8 is produced by our Mammalian expression system and the target gene encoding Arg28-Thr579 is expressed with a human IgG1 Fc tag at the C-terminus. |
Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
Molecular Weight | 90-120 KDa, reducing conditions |
Endotoxin | Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
Reconstitution | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Stability & Storage |
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
Shipping |
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
Research Background | Immunoglobulin Superfamily Member 8 (IGSF8) is a single-pass membrane protein. IGSF8 contains four Ig-like C2 type domains. The Ig-like C2-type domains 3 and 4 are required for interactions with CD81. IGSF8 may regulate proliferation and differentiation of keratinocytes. IGSF8 may participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain. It also may play a role on integrin-dependent morphology and motility functions. |
bottom
Please read the User Guide of Recombinant Proteins for more specific information.
CD316 Protein, Human, Recombinant (hFc) KCT-4 EWI2 CD81P3 KCT 4 CD316 IGSF8 Glu-Trp-Ile EWI Motif-Containing Protein 2 CD81 Partner 3 Keratinocytes-Associated Transmembrane Protein 4 CD-316 Immunoglobulin Superfamily Member 8 CD 316 PGRL IGSF 8 KCT4 IGSF-8 LIR-D1 EWI-2 Prostaglandin Regulatory-Like Protein EWI 2 recombinant recombinant-proteins proteins protein