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Anti-EpCAM/TROP1 Antibody (6T822) (Synonyms: TROP-1, TROP1, TACSTD1, MK-1, MIC18, M4S1, KSA, KS1/4, HNPC...)
Catalog No. TMAY-03374 Copy Product Info
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Anti-EpCAM/TROP1 Antibody (6T822) is a Rabbit antibody targeting EpCAM/TROP1. Anti-EpCAM/TROP1 Antibody (6T822) can be used in IHC-P.
Anti-EpCAM/TROP1 Antibody (6T822)
Copy Product Info🥰Excellent
Catalog No. TMAY-03374
Synonyms TROP-1, TROP1, TACSTD1, MK-1, MIC18, M4S1, KSA, KS1/4, HNPCC8, ESA, epithelial cell adhesion molecule, EGP40, EGP314, EGP-2, DIAR5
Anti-EpCAM/TROP1 Antibody (6T822) is a Rabbit antibody targeting EpCAM/TROP1. Anti-EpCAM/TROP1 Antibody (6T822) can be used in IHC-P.
Anti-EpCAM/TROP1 Antibody
(6T822)
(6T822)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 100 μL | $269 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-EpCAM/TROP1 Antibody (6T822) is a Rabbit antibody targeting EpCAM/TROP1. Anti-EpCAM/TROP1 Antibody (6T822) can be used in IHC-P. |
| Synonyms | TROP-1, TROP1, TACSTD1, MK-1, MIC18, M4S1, KSA, KS1/4, HNPCC8, ESA, epithelial cell adhesion molecule, EGP40, EGP314, EGP-2, DIAR5 |
| Ig Type | Rabbit IgG |
| Clone | 6T822 |
| Reactivity | Mouse |
| Specificity | Mouse EpCAM/TROP1 Has cross-reactivity in ELISA with Rat EPCAM No cross-reactivity in ELISA with Human EPCAM |
| Verified Activity | 1. Immunochemical staining of mouse EpCAM in mouse uterus with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of mouse EpCAM in mouse intestine with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). |
| Application | |
| Recommended Dose | IHC-P: 1:100-1:500 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse EpCAM / TROP-1 / TACSTD1 (rM EpCAM / TROP-1 / TACSTD1; TMPY-01766; NP_032558.2; Met1-Thr266). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Epithelial Cell Adhesion Molecule (EpCAM), also known as GA733-2 antigen, is a type I transmembrane glycoprotein composed of an extracellular domain with two EGF-Like repeats and a cystenin-rich region, a transmembrane domain and a cytoplasmic domain. It modulates cell adhesion and proliferation. Its overexpression has been detected in many epithelial tumours and has been associated with high stage, high grade and a worse survival in some tumour types. EpCAM has been shown to function as a calcium-independent homophilic cell adhesion molecule that does not exhibit any obvious relationship to the four known cell adhesion molecule superfamilies. However, recent insights have revealed that EpCAM participates in not only cell adhesion, but also in proliferation, migration and differentiation of cells. In addition, recent study revealed that EpCAM is the Wnt-beta-catenin signaling target gene and may be used to facilitate prognosis. It has oncogenic potential and is activated by release of its intracellular domain, which can signal into the cell nucleus by engagement of elements of the wnt pathway.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Mouse EpCAM / TROP-1 / TACSTD1 protein (TMPY-01766) |
| Antigen Species | Mouse |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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