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Anti-SEMA5A Polyclonal Antibody
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Catalog No. TMAB-01675
Alias serpin peptidase inhibitor, clade F, semF, SEMAF
Anti-SEMA5A Polyclonal Antibody is a Rabbit antibody targeting SEMA5A. Anti-SEMA5A Polyclonal Antibody can be used in WB.
Anti-SEMA5A Polyclonal Antibody
Anti-SEMA5A Polyclonal Antibody
😃Good
Catalog No. TMAB-01675Alias serpin peptidase inhibitor, clade F, semF, SEMAF
Anti-SEMA5A Polyclonal Antibody is a Rabbit antibody targeting SEMA5A. Anti-SEMA5A Polyclonal Antibody can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $221 | 7-10 days | |
| 100 μL | $372 | 7-10 days | |
| 200 μL | $529 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-SEMA5A Polyclonal Antibody is a Rabbit antibody targeting SEMA5A. Anti-SEMA5A Polyclonal Antibody can be used in WB. |
| Synonyms | serpin peptidase inhibitor, clade F, semF, SEMAF |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Chicken,Dog,Pig,Cow,Rabbit,Sheep,Zebrafish) |
| Verified Activity | Sample: A549 (Human) Cell Lysate at 30 μg Primary: Anti-Semaphorin 5A (TMAB-01675) at 1/500 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 118 kDa Observed band size: 118 kDa |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; single-pass type I membrane protein |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
| Concentration | 1 mg/mL |
| Research Background | This gene belongs to the semaphorin gene family that encodes membrane proteins containing a semaphorin domain and several thrombospondin type-1 repeats. Members of this family are involved in axonal guidance during neural development. This gene has been implicated as an autism susceptibility gene. |
| Immunogen | KLH conjugated synthetic peptide: human Semaphorin 5A |
| Antigen Species | Human |
| Gene Name | SEMA5A |
| Gene ID | |
| Protein Name | Semaphorin-5A |
| Uniprot ID | |
| Biology Area | Axonal Guidance Proteins,Neurogenesis,Neuroregeneration |
| Function | Bifunctional axonal guidance cue regulated by sulfated proteoglycans; attractive effects result from interactions with heparan sulfate proteoglycans (HSPGs), while the inhibitory effects depend on interactions with chondroitin sulfate proteoglycans (CSPGs) (By similarity). Ligand for receptor PLXNB3. In glioma cells, SEMA5A stimulation of PLXNB3 results in the disassembly of F-actin stress fibers, disruption of focal adhesions and cellular collapse as well as inhibition of cell migration and invasion through ARHGDIA-mediated inactivation of RAC1. May promote angiogenesis by increasing endothelial cell proliferation and migration and inhibiting apoptosis. |
| Molecular Weight | Theoretical: 118 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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