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GPR35 agonist 2 (Synonyms: TC-G 1001)

Name: GPR35 agonist 2
Brand: TargetMol
SKU: T23434
Price: 37 USD
Availability: InStock
Rating: 5 (10 reviews)

Catalog No. T23434 Copy Product Info

Purity: 99.53%

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GPR35 agonist 2 (TC-G 1001) is a potent GPR35 agonist.The EC50 values of GPR35 agonist 2 in the β-arrestin and Ca2+ release assays were 26 and 3.2 nM, respectively.

GPR35 agonist 2

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Catalog No. T23434

Synonyms TC-G 1001

GPR35 agonist 2 (TC-G 1001) is a potent GPR35 agonist.The EC50 values of GPR35 agonist 2 in the β-arrestin and Ca2+ release assays were 26 and 3.2 nM, respectively.

Cas No. 494191-73-0

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Pack Size	Price	USA Stock	Global Stock
2 mg	$37	In Stock	In Stock
5 mg	$58	In Stock	In Stock
10 mg	$107	In Stock	In Stock
25 mg	$238	In Stock	In Stock
50 mg	$353	In Stock	In Stock
100 mg	$506	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$70	In Stock	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Purity:99.53%

Appearance:Solid

Color:Yellow

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	GPR35 agonist 2 (TC-G 1001) is a potent GPR35 agonist.The EC50 values of GPR35 agonist 2 in the β-arrestin and Ca2+ release assays were 26 and 3.2 nM, respectively.
Targets&IC50	GPR35 (human, β arrestin):26 nM (EC50), GPR35 (human, Ca2+ release assay):3.2 nM (EC50)
Synonyms	TC-G 1001

Chemical Properties

Molecular Weight	342.34
Formula	C₁₇H₁₁FN₂O₃S
Cas No.	494191-73-0
Smiles	OC(=O)c1ccc(\C=C2\SC(Nc3ccccc3F)=NC2=O)cc1
Relative Density.	1.43 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 13 mg/mL (37.97 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.9211 mL	14.6054 mL	29.2107 mL	146.0536 mL
5 mM	0.5842 mL	2.9211 mL	5.8421 mL	29.2107 mL
10 mM	0.2921 mL	1.4605 mL	2.9211 mL	14.6054 mL
20 mM	0.1461 mL	0.7303 mL	1.4605 mL	7.3027 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc