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Synonyms: p58, NKAT2B, NKAT2A, NKAT2, NKAT, MGC129943, KIR-K7c, KIR-K7b, KIRCL23, KIR2DS5, KIR-023GB, killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3, GL183, CU464054.1, CD158B2, CD158b

| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $48 | - | In Stock | |
| 10 µg | $75 | - | In Stock | |
| 20 µg | $118 | - | In Stock | |
| 50 µg | $229 | - | In Stock | |
| 100 µg | $386 | - | In Stock | |
| 200 µg | $682 | 7-10 days | 7-10 days | |
| 500 µg | $1,430 | 7-10 days | 7-10 days |
| Bioactivity | Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | KIR2DL3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.9 kDa and the accession number is Q32WE4. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-His |
| Accession Number | Q32WE4 |
| Construction | A DNA sequence encoding the human KIR2DL3 (AAX23102.1) extracellular domain (Met 1-His 245) was fused with a polyhistidine tag at the C-terminus. Predicted N terminal: His 22 |
| Protein Purity | > 98 % as determined by SDS-PAGE ![]() |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
| Reconstitution | Reconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot. |
| Synonyms | p58, NKAT2B, NKAT2A, NKAT2, NKAT, MGC129943, KIR-K7c, KIR-K7b, KIRCL23, KIR2DS5, KIR-023GB, killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3, GL183, CU464054.1, CD158B2, CD158b |
| Research Background | Killer cell immunoglobulin-like receptor 2DL3, also known as CD158 antigen-like family member B2, KIR-23GB, Killer inhibitory receptor cl 2-3, MHC class I NK cell receptor, NKAT2a, NKAT2b, Natural killer-associated transcript 2, p58 natural killer cell receptor clone CL-6, p58.2 MHC class-I-specific NK receptor, CD158b2, and KIR2DL3, is a single-pass type I membrane protein which belongs to the immunoglobulin superfamily. KIR2DL3 contains 2 Ig-like C2-type (immunoglobulin-like) domains. KIR2DL3 interacts with ARRB2. KIR2DL3 is a receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3, and HLA-Cw7). KIR2DL3 inhibits the activity of NK cells thus preventing cell lysis. |
| Molecular Weight | 25.9 kDa (predicted); 45 kDa (reducing condition, due to glycosylation) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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