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GAPDH Loading Control Antibody (5Y774) is a Rabbit antibody targeting GAPDH. GAPDH Loading Control Antibody (5Y774) can be used in IHC-P.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
20 μL | 89 € | 7-10 days | |
100 μL | 176 € | 7-10 days |
Description | GAPDH Loading Control Antibody (5Y774) is a Rabbit antibody targeting GAPDH. GAPDH Loading Control Antibody (5Y774) can be used in IHC-P. |
Alias | HEL-S-162eP, glyceraldehyde-3-phosphate dehydrogenase, GAPD, G3PD |
Ig Type | Monoclonal Rabbit IgG |
Clone | 5Y774 |
Reactivity | Human |
Verified Activity | 1. Immunochemical staining of human GAPDH in human hepatitis with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human GAPDH in human appendicitis with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). |
Application | IHC-P |
Recommended Dose | IHC-P: 1:100-1:500 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with A synthetic peptide corresponding to the center region of the human GAPDH. |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Glyceraldehyde 3-phosphate dehydrogenase (GAPDH or G3PDH) is an enzyme of about 37kDa that is consisdered as a cellular enzyme involved in glycolysis. It catelyzes the sixth step of glycolysis. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a pleiotropic enzyme that is overexpressed in apoptosis and in several human chronic pathologies. Its role as a mediator for cell death has also been highlighted. A recent report suggests that GAPDH may be genetically associated with late-onset of Alzheimer's disease. Besides, deprenyl, which has originally been used as a monoamine oxidase inhibitor for Parkinson's disease, binds to GAPDH and displays neuroprotective actions. |
Conjucates | Unconjugated |
Immunogen | A synthetic peptide corresponding to the center region of the human GAPDH |
Antigen Species | Human |
Biology Area | Adaptor Proteins |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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