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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T28089 | MPGES-1 Inhibitor-1 | Prostaglandin Receptor | |
mPGES-1 Inhibitor-1 is a novel selective inhibitor of microsomal prostaglandin E synthase-1 (mPGES-1) with anti-inflammatory and analgesic activity for the study of acute liver injury. | |||
T11580 | Heme Oxygenase-1-IN-1 | HO-1-IN-1 | Reactive Oxygen Species |
Heme Oxygenase-1-IN-1 (HO-1-IN-1) is a heme oxygenase 1 (HO-1) inhibitor (IC50: 250 nM). | |||
T13147 | ICAM-1-IN-1 | Integrin | |
ICAM-1-IN-1 is a potent and selective E-selectin(IC50 = 7 nM) and ICAM-1(IC50 = 5 nM) inhibitor. | |||
T12910 | Sigma-1 receptor antagonist 1 | Sigma receptor | |
Sigma-1 receptor antagonist 1 is an effective and selective antagonist of sigma-1 receptor. Sigma-1 receptor antagonist 1 exhibits antineuropathic pain activity and can be used in the treatment of neuropathic pain studie... | |||
TN2295 | Vicenin-1 | Vicenin -1 | Antioxidant , Angiotensin-converting Enzyme (ACE) |
Vicenin-1 (Vicenin -1) is a flavonoid glycoside isolated from the seeds of the leguminous plant fenugreek with potent anti-inflammatory and antioxidant activity, inhibiting angiotensin-converting enzyme (ACE). | |||
T36432 | A2ti-1 | Virus Protease | |
A2ti-1 is a highly selective inhibitor of annexin A2/S100A10 heterotetramer (A2t) (IC50: 24 μM) that inhibits ARV-mediated activation of Src and p38 mitogen-activated protein kinase (MAPK). A2ti-1 can be used to study hu... | |||
T77506 | 1-vinylpyrene | 1-Ethenylpyrene | Others |
1-vinylpyrene (1-Ethenylpyrene) has antitumor activity and strongly inhibits the formation of skin tumors triggered by DMBA or B[]P in a dose-dependent manner and can be used to prevent tumor formation. | |||
TN6912 | 1-Nonanol | Nonan-1-ol | Antifungal |
1-Nonanol (Nonan-1-ol) is a fragrance with antifungal activity that acts by disrupting cell membrane integrity and mitochondrial function. | |||
T7888 | Enpp-1-IN-1 | PDE | |
Enpp-1-IN-1 is an inhibitor of Ectonucleotide pyrophosphatase-phosphodiesterase 1 (enpp-1) | |||
T6500 | Ferrostatin-1 | Ferrostatin 1,Ferrostatin-1 (Fer-1) | Ferroptosis , Antifungal |
Ferrostatin-1 (Fer-1) is a potent and selective inhibitor of iron death. Ferrostatin-1 potently inhibits Erastin-induced iron death in HT-1080 cells with an EC50 of 60 nM. Ferrostatin-1 also exhibits antioxidant and anti... | |||
T67928 | NDH-1 inhibitor-1 | Mitochondrial Metabolism | |
NDH-1 inhibitor-1 is an effective NDH-1 inhibitor, which can inhibit bovine SMP (mitochondrial granules), potato SMP and Escherichia coli, with pI50 values of <4, 5.40, 6.15 µM, respectively. | |||
T36821 | FQI 1 | Others | |
FQI 1 is an SV40 factor (LSF) inhibitor. FQI 1 inhibits cell proliferation, with IC50s of 3, 0.79, and 6.3 μM for NIH/3T3, HeLa, and A549 cells, respectively. FQI1 could be used in cancer research. | |||
T23716 | AMDE-1 | AMDE 1 | Autophagy |
AMDE-1 is an autophagy modulator and triggers autophagy in an Atg5-dependent manner. AMDE-1 recruits Atg16 to the pre-autophagosomal site and causes LC3 lipidation. | |||
T7411 | Rbin-1 | Ribozinoindole-1 | ATPase , Phosphatase |
Rbin-1 (Ribozinoindole-1) is a potent,specific inhibitor of eukaryotic ribosome biogenesis. | |||
T3655 | BMS-1 | PD1-PDL1 inhibitor 1,PD-1/PD-L1 inhibitor 1 | Apoptosis , PD-1/PD-L1 |
BMS-1 (PD-1/PD-L1 inhibitor 1) is an inhibitor of the PD1-PD-L1 protein-protein interaction. It also acts as an immunomodulator. Programmed death ligand 1 (PD-L1) is a protein in humans that is encoded by the CD274 gene ... | |||
T9314 | CC214-1 | mTOR , Autophagy | |
CC214-1 is an mTOR inhibitor with potential anticancer activity, inhibits protein translation, and induces autophagy. CC214-1 is an in vitro tool compound for exploring the biology of mTOR kinases and can be used to stud... | |||
T40112 | PROTAC PD-1/PD-L1 degrader-1 | PROTAC PD-1/PD-L1 degrader-1 | PROTACs |
PROTAC PD-1/PD-L1 degrader-1, a Cereblon E3 ligand-based compound, is a PD-1/PD-L1 PROTAC that effectively inhibits the interaction between PD-1 and PD-L1 with an IC50 value of 39.2 nM. It successfully restores the suppr... | |||
T2651 | IWR-1 | IWR-1-endo,endo-IWR 1 | Wnt/beta-catenin |
IWR-1 (IWR-1-endo), a Wnt pathway inhibitor, stabilizes the Axin destruction complex(EC50=0.2 uM). | |||
T24182 | ISX-1 | ISX 1 | Others |
ISX-1 inhibits adipogenesis and promotes osteoblastogenesis. ISX-1 can be used in studies about osteoporosis and osteopenia. | |||
T20067 | WST-1 | WST 1 | |
WST-1 is a cytotoxic, water-soluble tetrazolium salt that induces intracellular mitochondrial dehydrogenases to undergo NADH-dependent enzymatic reactions, releasing water-soluble methylbenzene products.WST-1 can be used... |