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Bruceoside A

Name: Bruceoside A
Brand: TargetMol
SKU: TN3543
Price: 139 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN3543Cas No. 63306-30-9

Bruceoside A is a bitter wood glycoside that can be isolated from opuntia and has anticancer and tumor activity and can be used with the study of leukemia.

Bruceoside A

🥰Excellent

Catalog No. TN3543Cas No. 63306-30-9

Bruceoside A is a bitter wood glycoside that can be isolated from opuntia and has anticancer and tumor activity and can be used with the study of leukemia.

Pack Size	Price	Availability
1 mg	$139	In Stock
5 mg	$345	In Stock
10 mg	$513	In Stock
25 mg	$833	In Stock
50 mg	$1,215	In Stock

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Batch Information

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Purity:>99.99%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Bruceoside A is a bitter wood glycoside that can be isolated from opuntia and has anticancer and tumor activity and can be used with the study of leukemia.
In vitro	Similar inhibitory effects on P-388 cell oxidative phosphorylation were found in vitro with brusatol, bruceoside A, and bruceantin[1].
In vivo	Bruceoside A can undergo transformation into the potent anticancer component brusatol in vivo, rather than being directly metabolized into its deglycosylated form, bruceosin[2].

Chemical Properties

Molecular Weight	682.67
Formula	C₃₂H₄₂O₁₆
Cas No.	63306-30-9
Smiles	C(OC)(=O)[C@]12[C@]3([C@]4([C@@]([C@]5(C)[C@@](C[C@]4(OC(=O)[C@@H]3OC(C=C(C)C)=O)[H])([C@H](C)C(=O)C(O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)=C5)[H])([C@@H](O)[C@@H]1O)[H])CO2)[H]
Relative Density.	1.55 g/cm3 (Predicted)

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (146.48 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.4648 mL	7.3242 mL	14.6484 mL	73.2418 mL
5 mM	0.2930 mL	1.4648 mL	2.9297 mL	14.6484 mL
10 mM	0.1465 mL	0.7324 mL	1.4648 mL	7.3242 mL
20 mM	0.0732 mL	0.3662 mL	0.7324 mL	3.6621 mL
50 mM	0.0293 mL	0.1465 mL	0.2930 mL	1.4648 mL
100 mM	0.0146 mL	0.0732 mL	0.1465 mL	0.7324 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc