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10-Undecenoic acid

Name: 10-Undecenoic acid
Brand: TargetMol
SKU: T0306
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T0306Cas No. 112-38-9

Alias Undecylenic acid, Undecenoic acid

10-Undecenoic acid (Undecylenic acid) is a natural or synthetic fungistatic fatty acid, with antifungal activity.

10-Undecenoic acid

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Purity: 99.58%

Catalog No. T0306Alias Undecylenic acid, Undecenoic acidCas No. 112-38-9

10-Undecenoic acid (Undecylenic acid) is a natural or synthetic fungistatic fatty acid, with antifungal activity.

Pack Size	Price	USA Warehouse	Global Warehouse
500 mg	$30	-	In Stock
1 g	$40	-	In Stock
5 g	$60	-	In Stock
10 g	$79	-	In Stock
25 g	$118	-	In Stock
1 mL x 10 mM (in DMSO)	$29	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Purity:99.58%

Color:Transparent

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Product Introduction

10-Undecenoic acid AI Summary

10-Undecenoic acid exhibits potent antifungal activity against a variety of fungal strains, including Candida albicans, Cryptococcus neoformans, Aspergillus niger, and various Trichophyton species, with IC50 values ranging from 2700.0 nM to 414900.0 nM and MIC values up to 542700.0 nM. Notably, it demonstrates a minimum fungicidal concentration (MFC) of 542.7 µM against Cryptococcus neoformans. In addition to its antifungal properties, 10-Undecenoic acid modulates Lamin A splicing with a potency of 0.8 nM, inhibits Tau fibril formation with a potency of 39810.7 nM, and displays growth inhibition activity against multiple human tumor cell lines (GI50 values ranging from 797.99 nM to 179060.59 nM). It effectively blocks Ebola virus entry with AC50 values between 0.631 µM and 631.0 nM. Furthermore, 10-Undecenoic acid inhibits human BSEP, MRP2, MRP3, and MRP4 transporters, showing weaker inhibition on MRP4 with an IC50 value of 63900.0 nM. It also exerts moderate inhibitory activity against human HDAC6, with variable enzyme activity reduction depending on the peptide substrate used in the assays. However, it shows low bioactivity in other assays, with AC50 values exceeding 30000.0 nM, indicating minimal activity against several tested targets. Overall, 10-Undecenoic acid demonstrates a diverse bioactivity profile, most notably its significant antifungal efficacy and inhibitory actions on specific molecular targets..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	10-Undecenoic acid (Undecylenic acid) is a natural or synthetic fungistatic fatty acid, with antifungal activity.
Synonyms	Undecylenic acid, Undecenoic acid

Chemical Properties

Molecular Weight	184.28
Formula	C₁₁H₂₀O₂
Cas No.	112-38-9
Smiles	C(CCCCC=C)CCCC(O)=O
Relative Density.	0.912 g/cm3 at 25℃ (lit.)

Storage & Solubility Information

Storage

Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 250 mg/mL (1356.63 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween-80+45% Saline: 2.5 mg/mL (13.57 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.4265 mL	27.1326 mL	54.2652 mL	271.3262 mL
5 mM	1.0853 mL	5.4265 mL	10.8530 mL	54.2652 mL
10 mM	0.5427 mL	2.7133 mL	5.4265 mL	27.1326 mL
20 mM	0.2713 mL	1.3566 mL	2.7133 mL	13.5663 mL
50 mM	0.1085 mL	0.5427 mL	1.0853 mL	5.4265 mL
100 mM	0.0543 mL	0.2713 mL	0.5427 mL	2.7133 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc