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ALDH1A3-IN-1 (Compound 14) is a potent inhibitor of ALDH1A3, with IC50 = 0.63 μM and Ki = 0.46 μM, and is utilized in prostate cancer research [1].

| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $30 | 7-10 days | |
| 5 mg | $82 | 7-10 days | |
| 10 mg | $125 | 7-10 days | |
| 25 mg | $247 | 7-10 days | |
| 50 mg | $392 | 7-10 days | |
| 100 mg | $650 | 7-10 days |
| Description | ALDH1A3-IN-1 (Compound 14) is a potent inhibitor of ALDH1A3, with IC50 = 0.63 μM and Ki = 0.46 μM, and is utilized in prostate cancer research [1]. |
| Targets&IC50 | ALDH1A3:0.46 μM (Ki), ALDH1A1:7.08 μM, ALDH1A3:26.92 μM (Km), ALDH3A1:8.00 μM, ALDH1A3:0.63 μM |
| In vitro | ALDH1A3-IN-1 (Compound 14) demonstrates significant antiproliferative effects on prostate cancer cell lines (PC3, LNCaP, and DU145) over a 96-hour treatment with IC50 values of 47 ± 6, 25 ± 1, and 61 ± 5 μM, respectively, at concentrations ranging from 0-200 μM [1]. Additionally, it reduces the viability of primary prostate epithelial cells from early-passage human tissue biopsies in a dose-dependent manner when administered at 50 and 200 μM for 72 hours, showcasing potential therapeutic action against prostate cancer [1]. |
| Molecular Weight | 284.19 |
| Formula | C13H18BrNO |
| Cas No. | 1695970-90-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |

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