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MF-438

🥰Excellent
Catalog No. T16068Cas No. 921605-87-0

MF-438 is an effective and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor (EC50: 2.3 nM for rSCD1).

MF-438

MF-438

🥰Excellent
Purity: 99.50%
Catalog No. T16068Cas No. 921605-87-0
MF-438 is an effective and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor (EC50: 2.3 nM for rSCD1).
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$98In StockIn Stock
2 mg$147In StockIn Stock
5 mg$226In StockIn Stock
10 mg$345In StockIn Stock
25 mg$586In StockIn Stock
50 mg$838In StockIn Stock
100 mg$1,160In StockIn Stock
500 mg$2,320-In Stock
1 mL x 10 mM (in DMSO)$248In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:99.50%
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COA LCMS HPLC HNMR

Product Introduction

Bioactivity
Description
MF-438 is an effective and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor (EC50: 2.3 nM for rSCD1).
Targets&IC50
SCD1 (rat):2.3 nM (EC50)
Chemical Properties
Molecular Weight421.44
FormulaC19H18F3N5OS
Cas No.921605-87-0
SmilesCc1nnc(s1)-c1ccc(nn1)N1CCC(CC1)Oc1ccccc1C(F)(F)F
Relative Density.1.365 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 45 mg/mL (106.78 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.3728 mL11.8641 mL23.7282 mL118.6409 mL
5 mM0.4746 mL2.3728 mL4.7456 mL23.7282 mL
10 mM0.2373 mL1.1864 mL2.3728 mL11.8641 mL
20 mM0.1186 mL0.5932 mL1.1864 mL5.9320 mL
50 mM0.0475 mL0.2373 mL0.4746 mL2.3728 mL
100 mM0.0237 mL0.1186 mL0.2373 mL1.1864 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

StearoylCoADesaturase(SCD)StearoylCoADesaturaseStearoyl-CoA Desaturase (SCD)StearoylCoA Desaturase (SCD)Stearoyl-CoA DesaturaseSCDrSCD1MF-438MF438MF 438Inhibitorinhibit
Related Tags: buy MF-438 | purchase MF-438 | MF-438 cost | order MF-438 | MF-438 chemical structure | MF-438 formula | MF-438 molecular weight
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