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Anti-ABCA1 Antibody (8N365) (Synonyms: TGD, TD, MGC165011, MGC164864, Membrane bound, HDLDT1, FLJ14958, C...)

Catalog No. TMAB-00020 Copy Product Info
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Anti-ABCA1 Antibody (8N365) is a Mouse antibody targeting ABCA1. Anti-ABCA1 Antibody (8N365) can be used in WB.

Anti-ABCA1 Antibody (8N365)

Copy Product Info
🥰Excellent
Catalog No. TMAB-00020
Synonyms TGD, TD, MGC165011, MGC164864, Membrane bound, HDLDT1, FLJ14958, Cholesterol Efflux Regulatory Protein, CERP, ATP-binding Cassette 1, ATP binding cassette transporter A1, ATP binding Cassette Transporter 1, ATP binding cassette sub family A member 1, ATP binding cassette sub family A ABC1 member 1, ATP binding Cassette 1, ABCA1, ABCA 1, ABC1, ABC Transporter 1, ABC 1

Anti-ABCA1 Antibody (8N365) is a Mouse antibody targeting ABCA1. Anti-ABCA1 Antibody (8N365) can be used in WB.

Anti-ABCA1 Antibody
(8N365)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1557-10 days7-10 days
50 μL$2727-10 days7-10 days
100 μL$4887-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-ABCA1 Antibody (8N365) is a Mouse antibody targeting ABCA1. Anti-ABCA1 Antibody (8N365) can be used in WB.
SynonymsTGD, TD, MGC165011, MGC164864, Membrane bound, HDLDT1, FLJ14958, Cholesterol Efflux Regulatory Protein, CERP, ATP-binding Cassette 1, ATP binding cassette transporter A1, ATP binding Cassette Transporter 1, ATP binding cassette sub family A member 1, ATP binding cassette sub family A ABC1 member 1, ATP binding Cassette 1, ABCA1, ABCA 1, ABC1, ABC Transporter 1, ABC 1
Ig Type
IgG
Clone
8N365
Reactivity
Mouse
Verified Activity
Blocking buffer: 5% NFDM/TBST
Primary dilution: 1:2000
Primary incubation condition: 2 hours at
room temperature
Lysate: Mouse liver
Protein loading quantity: 20 μg
Exposure time: 180 S
Predicted MW: 254 kDa
Observed MW: 254 kDa
verifiedActivity
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Monoclonal
Host SpeciesMouse
Subcellular LocalizationMembrane; Multi-pass membrane protein.
Tissue SpecificityWidely expressed, but most abundant in macrophages.
ConstructionRecombinant Antibody
PurificationProtein G purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1 mg/mL
Research BackgroundThe membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in both alleles of this gene cause Tangier disease and familial high-density lipoprotein (HDL) deficiency. [provided by RefSeq, Sep 2019]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: mouse ABCA1
Antigen Species
Mouse
Gene Name
ABCA1
Gene ID
Protein Name
phospholipid-transporting ATPase ABCA1
Uniprot ID
Biology Area
Metabolism of lipids and lipoproteins,Lipoprotein metabolism,Cholesterol Metabolism,Cholesterol Metabolism,Lipid metabolism,Lipoprotein metabolism,Cancer,Heart disease,Astrocyte marker,Lipid metabolism
Function
cAMP-dependent and sulfonylurea-sensitive anion transporter. Key gatekeeper influencing intracellular cholesterol transport.
Chemical Properties
Molecular WeightTheoretical: 254 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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