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Dimethylfraxetin

Name: Dimethylfraxetin
Brand: TargetMol
SKU: T4S2354
Price: 35 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T4S2354Cas No. 6035-49-0

Alias Fraxetin dimethyl ether, 6,7,8-Trimethoxycoumarin

Dimethylfraxetin (6,7,8-Trimethoxycoumarin) is a Carbonic anhydrase inhibitor(Ki:0.0097 μM)

Dimethylfraxetin

🥰Excellent

Purity: 99.96%

Catalog No. T4S2354Alias Fraxetin dimethyl ether, 6,7,8-TrimethoxycoumarinCas No. 6035-49-0

Dimethylfraxetin (6,7,8-Trimethoxycoumarin) is a Carbonic anhydrase inhibitor(Ki:0.0097 μM)

Pack Size	Price	Availability
1 mg	$35	In Stock
5 mg	$76	In Stock
10 mg	$136	In Stock
25 mg	$273	In Stock
50 mg	$392	In Stock
100 mg	$553	In Stock
1 mL x 10 mM (in DMSO)	$94	In Stock

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Batch Information

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Purity:99.96%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	Dimethylfraxetin (6,7,8-Trimethoxycoumarin) is a Carbonic anhydrase inhibitor(Ki:0.0097 μM)
Targets&IC50	CA:0.0097 μM（ki）
Synonyms	Fraxetin dimethyl ether, 6,7,8-Trimethoxycoumarin

Chemical Properties

Molecular Weight	236.22
Formula	C₁₂H₁₂O₅
Cas No.	6035-49-0
Smiles	COc1cc2ccc(=O)oc2c(OC)c1OC
Relative Density.	1.249 g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 125 mg/mL (529.17 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.2333 mL	21.1667 mL	42.3334 mL	211.6671 mL
5 mM	0.8467 mL	4.2333 mL	8.4667 mL	42.3334 mL
10 mM	0.4233 mL	2.1167 mL	4.2333 mL	21.1667 mL
20 mM	0.2117 mL	1.0583 mL	2.1167 mL	10.5834 mL
50 mM	0.0847 mL	0.4233 mL	0.8467 mL	4.2333 mL
100 mM	0.0423 mL	0.2117 mL	0.4233 mL	2.1167 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc