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TOPRelated productsBioactivityChemical infoStorage&SolubilityCalculator

1-Methyladenine

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Catalog No. T10018Cas No. 5142-22-3

1-Methyladenine is a DNA alkylation product that undergoes damage reversal through oxidative demethylation for repair purposes.

1-Methyladenine

1-Methyladenine

🥰Excellent
Catalog No. T10018Cas No. 5142-22-3
1-Methyladenine is a DNA alkylation product that undergoes damage reversal through oxidative demethylation for repair purposes.
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Product Introduction

Bioactivity
Description
1-Methyladenine is a DNA alkylation product that undergoes damage reversal through oxidative demethylation for repair purposes.
Chemical Properties
Molecular Weight149.15
FormulaC6H7N5
Cas No.5142-22-3
Relative Density.1.31g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 5.2 mg/mL (34.86 mM), Sonication and heating to 80℃ are recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM6.7047 mL33.5233 mL67.0466 mL335.2330 mL
5 mM1.3409 mL6.7047 mL13.4093 mL67.0466 mL
10 mM0.6705 mL3.3523 mL6.7047 mL33.5233 mL
20 mM0.3352 mL1.6762 mL3.3523 mL16.7616 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Human Endogenous Metabolite1-Methyladenine1Methyladenine1 Methyladenine
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